Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts

Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts

Parkinson’s Disease (PD) is characterized both by the loss of dopaminergic neurons in the substantia nigra and the presence of cytoplasmic inclusions called Lewy Bodies. These Lewy Bodies contain the aggregated α-synuclein (α-syn) protein, which has been shown to be able...

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Bibliographic Details
Main Authors: Margaux Teil, Marie-Laure Arotcarena, Emilie Faggiani, Florent Laferriere, Erwan Bezard, Benjamin Dehay
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
parkinson’s disease, α-synuclein
neurodegeneration
therapy
aggregation
Online Access:https://www.mdpi.com/2218-273X/10/3/391

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