Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review

Carotid artery atherosclerosis, the result of a multitude of vascular risk factors, is a promising marker for use in risk stratification. Recent evidence suggests that carotid artery atherosclerosis affects cognitive function and is an independent risk factor for the development of cognitive impairm...

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Main Authors: Håkon Ihle-Hansen, Hege Ihle-Hansen, Else Charlotte Sandset, Guri Hagberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.705043/full
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author Håkon Ihle-Hansen
Hege Ihle-Hansen
Hege Ihle-Hansen
Else Charlotte Sandset
Guri Hagberg
Guri Hagberg
author_facet Håkon Ihle-Hansen
Hege Ihle-Hansen
Hege Ihle-Hansen
Else Charlotte Sandset
Guri Hagberg
Guri Hagberg
author_sort Håkon Ihle-Hansen
collection DOAJ
description Carotid artery atherosclerosis, the result of a multitude of vascular risk factors, is a promising marker for use in risk stratification. Recent evidence suggests that carotid artery atherosclerosis affects cognitive function and is an independent risk factor for the development of cognitive impairment. Both atherosclerosis and cognitive impairment develop over a prolonged period (years), and due to the aging population, markers to identify persons at risk are needed. Carotid artery atherosclerosis can easily be visualized using non-invasive ultrasound, potentially enabling early and intensified risk factor management to preserve cognitive function or delay further decline. However, the burden of atherosclerosis and temporal exposure required to pose a risk of cognitive impairment is unclear. This mini-review aims to explore the available evidence on the association between carotid atherosclerosis and cognition, and furthermore identify the remaining gaps in knowledge.
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spelling doaj.art-1b0422f1fa694100ada1cd52643f735c2022-12-21T19:52:40ZengFrontiers Media S.A.Frontiers in Neurology1664-22952021-07-011210.3389/fneur.2021.705043705043Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-ReviewHåkon Ihle-Hansen0Hege Ihle-Hansen1Hege Ihle-Hansen2Else Charlotte Sandset3Guri Hagberg4Guri Hagberg5Department of Medicine, Bærum Hospital- Vestre Viken Hospital Trust, Drammen, NorwayDepartment of Medicine, Bærum Hospital- Vestre Viken Hospital Trust, Drammen, NorwayOslo Stroke Unit, Department of Neurology, Oslo University Hospital, Ullevål, NorwayOslo Stroke Unit, Department of Neurology, Oslo University Hospital, Ullevål, NorwayDepartment of Medicine, Bærum Hospital- Vestre Viken Hospital Trust, Drammen, NorwayOslo Stroke Unit, Department of Neurology, Oslo University Hospital, Ullevål, NorwayCarotid artery atherosclerosis, the result of a multitude of vascular risk factors, is a promising marker for use in risk stratification. Recent evidence suggests that carotid artery atherosclerosis affects cognitive function and is an independent risk factor for the development of cognitive impairment. Both atherosclerosis and cognitive impairment develop over a prolonged period (years), and due to the aging population, markers to identify persons at risk are needed. Carotid artery atherosclerosis can easily be visualized using non-invasive ultrasound, potentially enabling early and intensified risk factor management to preserve cognitive function or delay further decline. However, the burden of atherosclerosis and temporal exposure required to pose a risk of cognitive impairment is unclear. This mini-review aims to explore the available evidence on the association between carotid atherosclerosis and cognition, and furthermore identify the remaining gaps in knowledge.https://www.frontiersin.org/articles/10.3389/fneur.2021.705043/fullIMTcognitive functiondementiaplaquecarotid artery atherosclerosis
spellingShingle Håkon Ihle-Hansen
Hege Ihle-Hansen
Hege Ihle-Hansen
Else Charlotte Sandset
Guri Hagberg
Guri Hagberg
Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review
Frontiers in Neurology
IMT
cognitive function
dementia
plaque
carotid artery atherosclerosis
title Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review
title_full Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review
title_fullStr Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review
title_full_unstemmed Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review
title_short Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review
title_sort subclinical carotid artery atherosclerosis and cognitive function a mini review
topic IMT
cognitive function
dementia
plaque
carotid artery atherosclerosis
url https://www.frontiersin.org/articles/10.3389/fneur.2021.705043/full
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