Physical exercise as treatment for adults with type 2 diabetes: a rapid review
BackgroundType 2 diabetes mellitus (T2DM) is a leading cause of disability-adjusted life years (DALY). Physical exercise is an effective non-pharmacological intervention to promote glycaemic control in T2DM. However, the optimal exercise parameters for glycemic control in individuals with T2DM remai...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1233906/full |
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| author | Andressa Karoline Pinto de Lima Ribeiro Andressa Karoline Pinto de Lima Ribeiro Josilayne Patrícia Ramos Carvalho Josilayne Patrícia Ramos Carvalho Natáli Valim Oliver Bento-Torres Natáli Valim Oliver Bento-Torres Natáli Valim Oliver Bento-Torres |
| author_facet | Andressa Karoline Pinto de Lima Ribeiro Andressa Karoline Pinto de Lima Ribeiro Josilayne Patrícia Ramos Carvalho Josilayne Patrícia Ramos Carvalho Natáli Valim Oliver Bento-Torres Natáli Valim Oliver Bento-Torres Natáli Valim Oliver Bento-Torres |
| author_sort | Andressa Karoline Pinto de Lima Ribeiro |
| collection | DOAJ |
| description | BackgroundType 2 diabetes mellitus (T2DM) is a leading cause of disability-adjusted life years (DALY). Physical exercise is an effective non-pharmacological intervention to promote glycaemic control in T2DM. However, the optimal exercise parameters for glycemic control in individuals with T2DM remain unclear.ObjectiveThis study aimed to analyze the relationship between physical training variables – frequency, intensity, type, duration, volume, and progression – and glycemic control in individuals with T2DM.MethodsA rapid systematic literature review was conducted on PubMed and LILACS databases. The PICOT strategy was employed to define the inclusion criteria. Eligible studies had to assess the impact of exercise parameters (frequency, intensity, type, duration, volume, and progression) on glycemic control indicators, primarily glycosylated hemoglobin (HbA1c). Randomized and non-randomized clinical trials were included in the review. The methodological quality of each study was assessed using the PEDro scale (PROSPERO - CRD 42021262614).ResultsOut of 1188 papers initially identified, 18 reports met the inclusion criteria and were included in the analysis. A total of 1,228 participants with T2DM (1086 in exercise groups) were included in the selected studies. Among these studies, 16 (88.9%) were RCTs and 2 (11.1%) were nRCTs. The age of participants ranged from 43.1 and 68.9 years, and the average intervention duration was 16.8 weeks. Data on adherence to the intervention, adverse events, detailed intervention protocol, and its impacts on glycaemic control, lipid profile, blood pressure, anthropometric measures, medication, body composition, and physical fitness are reported.ConclusionThe evidence supports the safety and effectiveness of physical exercises as non-pharmacological interventions for glycemic control. Aerobic, resistance and combined training interventions were associated with reductions in HbA1c and fasting glucose. The diversity of the physical exercise intervention protocols investigated in the studies included in this review is an important limitation to generalizing evidence-based practice. The call for action is mandatory to implement large-scale education programs on the prevention of diabetes and public health policies aimed to include well-planned and supervised exercise programs as an essential part of the primary prevention of type 2 diabetes.Systematic Review RegistrationPROSPERO, identifier (CRD42021262614). |
| first_indexed | 2024-03-11T21:13:30Z |
| format | Article |
| id | doaj.art-1b0666c0eb764682bbc9119ab1aae4b1 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-11T21:13:30Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-1b0666c0eb764682bbc9119ab1aae4b12023-09-29T05:35:46ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-09-011410.3389/fendo.2023.12339061233906Physical exercise as treatment for adults with type 2 diabetes: a rapid reviewAndressa Karoline Pinto de Lima Ribeiro0Andressa Karoline Pinto de Lima Ribeiro1Josilayne Patrícia Ramos Carvalho2Josilayne Patrícia Ramos Carvalho3Natáli Valim Oliver Bento-Torres4Natáli Valim Oliver Bento-Torres5Natáli Valim Oliver Bento-Torres6Graduate Program in Attention and Clinical Study in Diabetes, Institute of Medical Sciences, Federal University of Pará, Belém, Pará, BrazilNeurodegeneration and Infection Research Laboratory, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, BrazilNeurodegeneration and Infection Research Laboratory, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, BrazilGraduate Program in Human Movement Sciences, Institute of Health Sciences, Federal University of Pará, Belém, BrazilGraduate Program in Attention and Clinical Study in Diabetes, Institute of Medical Sciences, Federal University of Pará, Belém, Pará, BrazilNeurodegeneration and Infection Research Laboratory, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, BrazilGraduate Program in Human Movement Sciences, Institute of Health Sciences, Federal University of Pará, Belém, BrazilBackgroundType 2 diabetes mellitus (T2DM) is a leading cause of disability-adjusted life years (DALY). Physical exercise is an effective non-pharmacological intervention to promote glycaemic control in T2DM. However, the optimal exercise parameters for glycemic control in individuals with T2DM remain unclear.ObjectiveThis study aimed to analyze the relationship between physical training variables – frequency, intensity, type, duration, volume, and progression – and glycemic control in individuals with T2DM.MethodsA rapid systematic literature review was conducted on PubMed and LILACS databases. The PICOT strategy was employed to define the inclusion criteria. Eligible studies had to assess the impact of exercise parameters (frequency, intensity, type, duration, volume, and progression) on glycemic control indicators, primarily glycosylated hemoglobin (HbA1c). Randomized and non-randomized clinical trials were included in the review. The methodological quality of each study was assessed using the PEDro scale (PROSPERO - CRD 42021262614).ResultsOut of 1188 papers initially identified, 18 reports met the inclusion criteria and were included in the analysis. A total of 1,228 participants with T2DM (1086 in exercise groups) were included in the selected studies. Among these studies, 16 (88.9%) were RCTs and 2 (11.1%) were nRCTs. The age of participants ranged from 43.1 and 68.9 years, and the average intervention duration was 16.8 weeks. Data on adherence to the intervention, adverse events, detailed intervention protocol, and its impacts on glycaemic control, lipid profile, blood pressure, anthropometric measures, medication, body composition, and physical fitness are reported.ConclusionThe evidence supports the safety and effectiveness of physical exercises as non-pharmacological interventions for glycemic control. Aerobic, resistance and combined training interventions were associated with reductions in HbA1c and fasting glucose. The diversity of the physical exercise intervention protocols investigated in the studies included in this review is an important limitation to generalizing evidence-based practice. The call for action is mandatory to implement large-scale education programs on the prevention of diabetes and public health policies aimed to include well-planned and supervised exercise programs as an essential part of the primary prevention of type 2 diabetes.Systematic Review RegistrationPROSPERO, identifier (CRD42021262614). https://www.frontiersin.org/articles/10.3389/fendo.2023.1233906/fulldiabetes mellitusphysical exercise, rehabilitationglycemic controlprimary health carequality of lifephysical fitness |
| spellingShingle | Andressa Karoline Pinto de Lima Ribeiro Andressa Karoline Pinto de Lima Ribeiro Josilayne Patrícia Ramos Carvalho Josilayne Patrícia Ramos Carvalho Natáli Valim Oliver Bento-Torres Natáli Valim Oliver Bento-Torres Natáli Valim Oliver Bento-Torres Physical exercise as treatment for adults with type 2 diabetes: a rapid review Frontiers in Endocrinology diabetes mellitus physical exercise, rehabilitation glycemic control primary health care quality of life physical fitness |
| title | Physical exercise as treatment for adults with type 2 diabetes: a rapid review |
| title_full | Physical exercise as treatment for adults with type 2 diabetes: a rapid review |
| title_fullStr | Physical exercise as treatment for adults with type 2 diabetes: a rapid review |
| title_full_unstemmed | Physical exercise as treatment for adults with type 2 diabetes: a rapid review |
| title_short | Physical exercise as treatment for adults with type 2 diabetes: a rapid review |
| title_sort | physical exercise as treatment for adults with type 2 diabetes a rapid review |
| topic | diabetes mellitus physical exercise, rehabilitation glycemic control primary health care quality of life physical fitness |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1233906/full |
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