Nanomaterials as Promising Alternative in the Infection Treatment
Both the prevalence of antibiotic resistance and the increased biofilm-associated infections are boosting the demand for new advanced and more effective treatment for such infections. In this sense, nanotechnology offers a ground-breaking platform for addressing this challenge. This review shows the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-08-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/20/15/3806 |
| _version_ | 1811221937625497600 |
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| author | María Vallet-Regí Blanca González Isabel Izquierdo-Barba |
| author_facet | María Vallet-Regí Blanca González Isabel Izquierdo-Barba |
| author_sort | María Vallet-Regí |
| collection | DOAJ |
| description | Both the prevalence of antibiotic resistance and the increased biofilm-associated infections are boosting the demand for new advanced and more effective treatment for such infections. In this sense, nanotechnology offers a ground-breaking platform for addressing this challenge. This review shows the current progress in the field of antimicrobial inorganic-based nanomaterials and their activity against bacteria and bacterial biofilm. Herein, nanomaterials preventing the bacteria adhesion and nanomaterials treating the infection once formed are presented through a classification based on their functionality. To fight infection, nanoparticles with inherent antibacterial activity and nanoparticles acting as nanovehicles are described, emphasizing the design of the carrier nanosystems with properties targeting the bacteria and the biofilm. |
| first_indexed | 2024-04-12T08:08:33Z |
| format | Article |
| id | doaj.art-1b08b3d2800a411091e7962ebb6f3e37 |
| institution | Directory Open Access Journal |
| issn | 1422-0067 |
| language | English |
| last_indexed | 2024-04-12T08:08:33Z |
| publishDate | 2019-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-1b08b3d2800a411091e7962ebb6f3e372022-12-22T03:41:03ZengMDPI AGInternational Journal of Molecular Sciences1422-00672019-08-012015380610.3390/ijms20153806ijms20153806Nanomaterials as Promising Alternative in the Infection TreatmentMaría Vallet-Regí0Blanca González1Isabel Izquierdo-Barba2Departamento de Química en Ciencias Farmacéuticas, Unidad de Química Inorgánica y Bioinorgánica, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n, Madrid 28040, SpainDepartamento de Química en Ciencias Farmacéuticas, Unidad de Química Inorgánica y Bioinorgánica, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n, Madrid 28040, SpainDepartamento de Química en Ciencias Farmacéuticas, Unidad de Química Inorgánica y Bioinorgánica, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n, Madrid 28040, SpainBoth the prevalence of antibiotic resistance and the increased biofilm-associated infections are boosting the demand for new advanced and more effective treatment for such infections. In this sense, nanotechnology offers a ground-breaking platform for addressing this challenge. This review shows the current progress in the field of antimicrobial inorganic-based nanomaterials and their activity against bacteria and bacterial biofilm. Herein, nanomaterials preventing the bacteria adhesion and nanomaterials treating the infection once formed are presented through a classification based on their functionality. To fight infection, nanoparticles with inherent antibacterial activity and nanoparticles acting as nanovehicles are described, emphasizing the design of the carrier nanosystems with properties targeting the bacteria and the biofilm.https://www.mdpi.com/1422-0067/20/15/3806preventing infectionzwitterionic surfacesnanopattering surfacesnanoparticlesmesoporous silica nanoparticlesantibacterial activitytargeting |
| spellingShingle | María Vallet-Regí Blanca González Isabel Izquierdo-Barba Nanomaterials as Promising Alternative in the Infection Treatment International Journal of Molecular Sciences preventing infection zwitterionic surfaces nanopattering surfaces nanoparticles mesoporous silica nanoparticles antibacterial activity targeting |
| title | Nanomaterials as Promising Alternative in the Infection Treatment |
| title_full | Nanomaterials as Promising Alternative in the Infection Treatment |
| title_fullStr | Nanomaterials as Promising Alternative in the Infection Treatment |
| title_full_unstemmed | Nanomaterials as Promising Alternative in the Infection Treatment |
| title_short | Nanomaterials as Promising Alternative in the Infection Treatment |
| title_sort | nanomaterials as promising alternative in the infection treatment |
| topic | preventing infection zwitterionic surfaces nanopattering surfaces nanoparticles mesoporous silica nanoparticles antibacterial activity targeting |
| url | https://www.mdpi.com/1422-0067/20/15/3806 |
| work_keys_str_mv | AT mariavalletregi nanomaterialsaspromisingalternativeintheinfectiontreatment AT blancagonzalez nanomaterialsaspromisingalternativeintheinfectiontreatment AT isabelizquierdobarba nanomaterialsaspromisingalternativeintheinfectiontreatment |