Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literature

<p>The indications for transfusion of blood components support after stem cell transplantation (SCT) usually do not differ form other clinical situations, but the rules for such therapy have a number of features. One of them is the possibility of inconsistence of AB0 group between donor and re...

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Main Authors: D. N. Balashov, P. E. Trakhtman
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Онкогематология
Subjects:
Online Access:http://oncohematology.abvpress.ru/index.php/ongm/article/view/25
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author D. N. Balashov
P. E. Trakhtman
author_facet D. N. Balashov
P. E. Trakhtman
author_sort D. N. Balashov
collection DOAJ
description <p>The indications for transfusion of blood components support after stem cell transplantation (SCT) usually do not differ form other clinical situations, but the rules for such therapy have a number of features. One of them is the possibility of inconsistence of AB0 group between donor and recipient of hematopoietic stem cells, which is not only fraught with the development of various alloimmune complications, but also fundamentally changes the standards for the selection of blood components for transfusion. A major problem after HSCT is a secondary immunodeficiency, which is important to consider for ensuring prevention of transfusion-transmitted infections (eg, CMV), as well as to carry out activities aimed for the prevention of transfusion- associated graft-versus-host disease. HSCT is a medical technology today, the effectiveness of which is often dependent on the accuracy and integrity of its implementation. So, serious attitude to various supportive therapy, including transfusions of blood components is an important component which determines the success of the treatment.</p>
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spelling doaj.art-1b0bd770d1a54ee2afc8ac798496e3602023-02-02T06:33:41ZrusABV-pressОнкогематология1818-83462014-07-0183424740Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literatureD. N. Balashov0P. E. Trakhtman1Dmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of RussiaDmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia<p>The indications for transfusion of blood components support after stem cell transplantation (SCT) usually do not differ form other clinical situations, but the rules for such therapy have a number of features. One of them is the possibility of inconsistence of AB0 group between donor and recipient of hematopoietic stem cells, which is not only fraught with the development of various alloimmune complications, but also fundamentally changes the standards for the selection of blood components for transfusion. A major problem after HSCT is a secondary immunodeficiency, which is important to consider for ensuring prevention of transfusion-transmitted infections (eg, CMV), as well as to carry out activities aimed for the prevention of transfusion- associated graft-versus-host disease. HSCT is a medical technology today, the effectiveness of which is often dependent on the accuracy and integrity of its implementation. So, serious attitude to various supportive therapy, including transfusions of blood components is an important component which determines the success of the treatment.</p>http://oncohematology.abvpress.ru/index.php/ongm/article/view/25hemopoietic stem cell transplantationtransfusion therapy,hemolysisalloimmunizationtransfusion-associated graft-versushost disease
spellingShingle D. N. Balashov
P. E. Trakhtman
Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literature
Онкогематология
hemopoietic stem cell transplantation
transfusion therapy,
hemolysis
alloimmunization
transfusion-associated graft-versushost disease
title Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literature
title_full Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literature
title_fullStr Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literature
title_full_unstemmed Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literature
title_short Features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation. Review of the literature
title_sort features of transfusion therapy in patients undergoing hematopoietic stem cell transplantation review of the literature
topic hemopoietic stem cell transplantation
transfusion therapy,
hemolysis
alloimmunization
transfusion-associated graft-versushost disease
url http://oncohematology.abvpress.ru/index.php/ongm/article/view/25
work_keys_str_mv AT dnbalashov featuresoftransfusiontherapyinpatientsundergoinghematopoieticstemcelltransplantationreviewoftheliterature
AT petrakhtman featuresoftransfusiontherapyinpatientsundergoinghematopoieticstemcelltransplantationreviewoftheliterature