Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland

Introduction and Objective: Obesity, as one of the diseases of civilization, has become a significant problem in our time. Although the first ways of treating it appeared many years ago, pharmacotherapy of obesity has been developing significantly in recent years. The purpose of this article is t...

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Main Authors: Barbara Woch, Dawid Bereza, Katarzyna Sokołowska, Maria Kulak, Igor Moreau, Paulina Polańska, Miriam Lang
Format: Article
Language:English
Published: Kazimierz Wielki University 2024-02-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/48026
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author Barbara Woch
Dawid Bereza
Katarzyna Sokołowska
Maria Kulak
Igor Moreau
Paulina Polańska
Miriam Lang
author_facet Barbara Woch
Dawid Bereza
Katarzyna Sokołowska
Maria Kulak
Igor Moreau
Paulina Polańska
Miriam Lang
author_sort Barbara Woch
collection DOAJ
description Introduction and Objective: Obesity, as one of the diseases of civilization, has become a significant problem in our time. Although the first ways of treating it appeared many years ago, pharmacotherapy of obesity has been developing significantly in recent years. The purpose of this article is to introduce the obesity drugs that have been registered for the treatment of obesity in Poland and to describe a new substance called tirzepatide, which, although it does not have such registration yet, is one of the most promising medications of the near future.   State of Knowledge: Obesity is an urgent and growing problem. In Poland, about 25% of adults are obese, and this number is increasing over the years. In Europe, four drugs belonging to three different groups are registered for the treatment of obesity: orlistat, a combined drug that includes naltrexone hydrochloride and bupropion hydrochloride, liraglutide, and semaglutide. Although the last drug achieves the best results in studies and is the substance most favored by doctors and patients, there is still much research on new substances and formulations, which would bring even better results and health benefits. One of these substances is tirzepatide, a drug registered in 2022 for the treatment of type 2 diabetes.   Summary: Nowadays in Poland, there are four drugs registered for obesity. Two of them are representatives of the group of GLP-1 analogues.  Pharmacological treatment of obesity has good results and is a relatively safe process that should be implemented in conjunction with lifestyle changes. The fifth substance described in this article is tirzepatide, a drug that, although not registered for the treatment of obesity yet,  is for now one of the most promising substances among the new drugs.
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spelling doaj.art-1b0e0d172b8842babcd8c40c639412902024-02-10T11:52:51ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-02-015810.12775/JEHS.2024.58.004Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in PolandBarbara Woch0Dawid Bereza1Katarzyna Sokołowska2Maria Kulak3Igor Moreau4Paulina Polańska5Miriam Lang6Poviat Hospital Complex; Poviat Hospital in Oleśnica, Armii Krajowej 1, 56-400 Oleśnica; Poland;Dr Alfred Sokolowski Specialist Hospital in Walbrzych, A. Sokołowskiego 4, 58-309 Walbrzych, Poland Dr Alfred Sokolowski Specialist Hospital in Walbrzych, A. Sokołowskiego 4, 58-309 Walbrzych, PolandPomeranian Hospitals LLC, Polish Red Cross Maritime Hospital, Powstania Styczniowego 1, 81-519 Gdynia, PolandDivision of Pathophysiology, Department of Physiology and Pathophysiology, Wroclaw Medical University, Tytusa Chałubińskiego 10, 50-368 Wroclaw, PolandFaculty of Medicine, Wroclaw Medical University, Wybrzeże L. Pasteura 1, 50-367 Wroclaw, PolandLower Silesian Oncology Centre, Plac Ludwika Hirszfelda 12, 53-413 Wrocław, Poland Introduction and Objective: Obesity, as one of the diseases of civilization, has become a significant problem in our time. Although the first ways of treating it appeared many years ago, pharmacotherapy of obesity has been developing significantly in recent years. The purpose of this article is to introduce the obesity drugs that have been registered for the treatment of obesity in Poland and to describe a new substance called tirzepatide, which, although it does not have such registration yet, is one of the most promising medications of the near future.   State of Knowledge: Obesity is an urgent and growing problem. In Poland, about 25% of adults are obese, and this number is increasing over the years. In Europe, four drugs belonging to three different groups are registered for the treatment of obesity: orlistat, a combined drug that includes naltrexone hydrochloride and bupropion hydrochloride, liraglutide, and semaglutide. Although the last drug achieves the best results in studies and is the substance most favored by doctors and patients, there is still much research on new substances and formulations, which would bring even better results and health benefits. One of these substances is tirzepatide, a drug registered in 2022 for the treatment of type 2 diabetes.   Summary: Nowadays in Poland, there are four drugs registered for obesity. Two of them are representatives of the group of GLP-1 analogues.  Pharmacological treatment of obesity has good results and is a relatively safe process that should be implemented in conjunction with lifestyle changes. The fifth substance described in this article is tirzepatide, a drug that, although not registered for the treatment of obesity yet,  is for now one of the most promising substances among the new drugs. https://apcz.umk.pl/JEHS/article/view/48026Anti-obesity agentsGLP-1 receptor agonistsweight lossoverweightobesityhealthy lifestyle
spellingShingle Barbara Woch
Dawid Bereza
Katarzyna Sokołowska
Maria Kulak
Igor Moreau
Paulina Polańska
Miriam Lang
Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland
Journal of Education, Health and Sport
Anti-obesity agents
GLP-1 receptor agonists
weight loss
overweight
obesity
healthy lifestyle
title Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland
title_full Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland
title_fullStr Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland
title_full_unstemmed Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland
title_short Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland
title_sort pharmacological treatment of obesity an overview of different groups of anti obesity drugs available in poland
topic Anti-obesity agents
GLP-1 receptor agonists
weight loss
overweight
obesity
healthy lifestyle
url https://apcz.umk.pl/JEHS/article/view/48026
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