KIF15 Promotes Progression of Castration Resistant Prostate Cancer by Activating EGFR Signaling Pathway

KIF15 Promotes Progression of Castration Resistant Prostate Cancer by Activating EGFR Signaling Pathway

Castration-resistant prostate cancer (CRPC) continues to be a major clinical problem and its underlying mechanisms are still not fully understood. The epidermal growth factor receptor (EGFR) activation is an important event that regulates mitogenic signaling. EGFR signaling plays an important role i...

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Bibliographic Details
Main Authors: Lin Gao, Ru Zhao, Junmei Liu, Wenbo Zhang, Feifei Sun, Qianshuo Yin, Xin Wang, Meng Wang, Tingting Feng, Yiming Qin, Wenjie Cai, Qianni Li, Hanchen Dong, Xueqing Chen, Xueting Xiong, Hui Liu, Jing Hu, Weiwen Chen, Bo Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Oncology
Subjects:
KIF15
EGFR
Cdc42
CRPC
protein stability
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.679173/full

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