In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular muscles
Abstract Background The accuracy of the surgical amount of extraocular muscle (EOM) is key to the success of strabismus surgery. To establish an accurate eye movement model, it is of great theoretical value and clinical significance to determine the surgical amount of EOM. At present, only resistanc...
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| Format: | Article |
| Language: | English |
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BMC
2019-05-01
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| Series: | BioMedical Engineering OnLine |
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| Online Access: | http://link.springer.com/article/10.1186/s12938-019-0688-4 |
| _version_ | 1818354346983686144 |
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| author | Hongmei Guo Zhipeng Gao Baoyan Han Lijun Zhang Zhaoqiang Tang Jing Chen Lili Wang Weiyi Chen |
| author_facet | Hongmei Guo Zhipeng Gao Baoyan Han Lijun Zhang Zhaoqiang Tang Jing Chen Lili Wang Weiyi Chen |
| author_sort | Hongmei Guo |
| collection | DOAJ |
| description | Abstract Background The accuracy of the surgical amount of extraocular muscle (EOM) is key to the success of strabismus surgery. To establish an accurate eye movement model, it is of great theoretical value and clinical significance to determine the surgical amount of EOM. At present, only resistance and stiffness data of orbital suspension tissues with EOMs exist, while those of orbital suspension tissues without EOMs, which is critical information for eye movement modeling, have not been reported. The aim of this research is to study the resistance and stiffness of orbital suspension tissues with/without EOMs. Methods Fifteen healthy New Zealand white rabbits with body weights of 2.41 ± 0.13 kg were used in the study. Two recti (two horizontal recti of the left eye or two vertical recti of the right eye) or all EOMs were detached from each eye under general anesthesia. Then, a 5-0 silk suture was attached to the stump of the detached rectus insertion (two horizontal recti insertions of the left eye and two vertical recti insertions of the right eye) on the isolated eyeball. The 5-0 silk suture was connected to the INSTRON 5544 tester to facilitate the horizontal rotations of the left eyes and the vertical rotations of the right eyes, respectively. Results The resistance and stiffness of orbital suspension tissues with superior rectus, inferior rectus, superior oblique, and inferior oblique EOMs were obtained during horizontal eye movement. Similarly, the resistance and stiffness of orbital suspension tissues with lateral rectus, medial rectus, superior oblique, and inferior oblique EOMs were obtained during vertical eye movement. Then, the resistance and stiffness of orbital suspension tissues without EOMs were obtained during horizontal and vertical eye movements. The resistance and stiffness data of orbital suspension tissues with EOMs were compared with those of orbital suspension tissues without EOMs. The comparison results showed no significant difference in the resistance values between these two cases. In addition, the stiffness values of these two cases statistically differed. Conclusions The two horizontal recti play a major role in passive horizontal eye movement. In addition, when the eye is passively moved vertically, the two vertical recti play major roles. The stiffness of orbital suspension tissues with EOMs, which has been used in eye movement modeling, is not accurate. The results of this work may serve as a reference for improving the accuracy in eye movement modeling, and then it will be beneficial for determining the surgical amount of EOMs in clinical surgery. |
| first_indexed | 2024-12-13T19:23:58Z |
| format | Article |
| id | doaj.art-1b16013e664b4b52ae24729c4cc8fbfd |
| institution | Directory Open Access Journal |
| issn | 1475-925X |
| language | English |
| last_indexed | 2024-12-13T19:23:58Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
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| series | BioMedical Engineering OnLine |
| spelling | doaj.art-1b16013e664b4b52ae24729c4cc8fbfd2022-12-21T23:34:05ZengBMCBioMedical Engineering OnLine1475-925X2019-05-0118111110.1186/s12938-019-0688-4In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular musclesHongmei Guo0Zhipeng Gao1Baoyan Han2Lijun Zhang3Zhaoqiang Tang4Jing Chen5Lili Wang6Weiyi Chen7Shanxi Key Laboratory of Material Strength & Structural Impact, College of Biomedical Engineering, Taiyuan University of TechnologyShanxi Key Laboratory of Material Strength & Structural Impact, College of Biomedical Engineering, Taiyuan University of TechnologyDepartment of Ophthalmology, Bethune International Peace Hospital of PLADepartment of Strabismus and Pediatric Ophthalmology, Shanxi Eye HospitalDepartment of Strabismus and Pediatric Ophthalmology, Shanxi Eye HospitalShanxi Key Laboratory of Material Strength & Structural Impact, College of Biomedical Engineering, Taiyuan University of TechnologyShanxi Key Laboratory of Material Strength & Structural Impact, College of Biomedical Engineering, Taiyuan University of TechnologyShanxi Key Laboratory of Material Strength & Structural Impact, College of Biomedical Engineering, Taiyuan University of TechnologyAbstract Background The accuracy of the surgical amount of extraocular muscle (EOM) is key to the success of strabismus surgery. To establish an accurate eye movement model, it is of great theoretical value and clinical significance to determine the surgical amount of EOM. At present, only resistance and stiffness data of orbital suspension tissues with EOMs exist, while those of orbital suspension tissues without EOMs, which is critical information for eye movement modeling, have not been reported. The aim of this research is to study the resistance and stiffness of orbital suspension tissues with/without EOMs. Methods Fifteen healthy New Zealand white rabbits with body weights of 2.41 ± 0.13 kg were used in the study. Two recti (two horizontal recti of the left eye or two vertical recti of the right eye) or all EOMs were detached from each eye under general anesthesia. Then, a 5-0 silk suture was attached to the stump of the detached rectus insertion (two horizontal recti insertions of the left eye and two vertical recti insertions of the right eye) on the isolated eyeball. The 5-0 silk suture was connected to the INSTRON 5544 tester to facilitate the horizontal rotations of the left eyes and the vertical rotations of the right eyes, respectively. Results The resistance and stiffness of orbital suspension tissues with superior rectus, inferior rectus, superior oblique, and inferior oblique EOMs were obtained during horizontal eye movement. Similarly, the resistance and stiffness of orbital suspension tissues with lateral rectus, medial rectus, superior oblique, and inferior oblique EOMs were obtained during vertical eye movement. Then, the resistance and stiffness of orbital suspension tissues without EOMs were obtained during horizontal and vertical eye movements. The resistance and stiffness data of orbital suspension tissues with EOMs were compared with those of orbital suspension tissues without EOMs. The comparison results showed no significant difference in the resistance values between these two cases. In addition, the stiffness values of these two cases statistically differed. Conclusions The two horizontal recti play a major role in passive horizontal eye movement. In addition, when the eye is passively moved vertically, the two vertical recti play major roles. The stiffness of orbital suspension tissues with EOMs, which has been used in eye movement modeling, is not accurate. The results of this work may serve as a reference for improving the accuracy in eye movement modeling, and then it will be beneficial for determining the surgical amount of EOMs in clinical surgery.http://link.springer.com/article/10.1186/s12938-019-0688-4Orbital suspension tissueResistanceStiffnessRabbit |
| spellingShingle | Hongmei Guo Zhipeng Gao Baoyan Han Lijun Zhang Zhaoqiang Tang Jing Chen Lili Wang Weiyi Chen In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular muscles BioMedical Engineering OnLine Orbital suspension tissue Resistance Stiffness Rabbit |
| title | In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular muscles |
| title_full | In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular muscles |
| title_fullStr | In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular muscles |
| title_full_unstemmed | In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular muscles |
| title_short | In vivo experimental study on the resistance and stiffness of orbital suspension tissues with/without the extraocular muscles |
| title_sort | in vivo experimental study on the resistance and stiffness of orbital suspension tissues with without the extraocular muscles |
| topic | Orbital suspension tissue Resistance Stiffness Rabbit |
| url | http://link.springer.com/article/10.1186/s12938-019-0688-4 |
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