Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa

We report a 7-year-old girl with xeroderma pigmentosum (XP), who presented in our clinic with a large melanoma (35 × 50 × 20 mm, Breslow depth 18 mm) in the zygomatic-malar area. Palliative surgery was performed to maintain her residual vision and to reduce the pain caused by the compression of loca...

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Main Authors: Kamlen Pillay, MBChB, Saleigh Adams, MBChB, FC Plast Surg, Laura Vandermaesen, MD, Donald Anthony Hudson, MBChB, MMed, FRCS
Format: Article
Language:English
Published: Wolters Kluwer 2017-08-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001442
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author Kamlen Pillay, MBChB
Saleigh Adams, MBChB, FC Plast Surg
Laura Vandermaesen, MD
Donald Anthony Hudson, MBChB, MMed, FRCS
author_facet Kamlen Pillay, MBChB
Saleigh Adams, MBChB, FC Plast Surg
Laura Vandermaesen, MD
Donald Anthony Hudson, MBChB, MMed, FRCS
author_sort Kamlen Pillay, MBChB
collection DOAJ
description We report a 7-year-old girl with xeroderma pigmentosum (XP), who presented in our clinic with a large melanoma (35 × 50 × 20 mm, Breslow depth 18 mm) in the zygomatic-malar area. Palliative surgery was performed to maintain her residual vision and to reduce the pain caused by the compression of local structures. Because of the limited access of autologous skin grafts in pediatric patients with XP who are severely affected, we opted to use an acellular dermal matrix. There was 100% graft uptake, and the pain due to compression by the tumor was alleviated. This case demonstrates that acellular dermal matrices can be safely and effectively used in oncological facial reconstruction, especially in patients with progressive conditions such as XP.
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spelling doaj.art-1b164e26c4744e2198acbc8dbe19a00c2022-12-22T01:28:53ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742017-08-0158e144210.1097/GOX.0000000000001442201708000-00018Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma PigmentosaKamlen Pillay, MBChB0Saleigh Adams, MBChB, FC Plast Surg1Laura Vandermaesen, MD2Donald Anthony Hudson, MBChB, MMed, FRCS3From the Department of Plastic and Reconstructive Surgery, University of Cape Town, South Africa.From the Department of Plastic and Reconstructive Surgery, University of Cape Town, South Africa.From the Department of Plastic and Reconstructive Surgery, University of Cape Town, South Africa.From the Department of Plastic and Reconstructive Surgery, University of Cape Town, South Africa.We report a 7-year-old girl with xeroderma pigmentosum (XP), who presented in our clinic with a large melanoma (35 × 50 × 20 mm, Breslow depth 18 mm) in the zygomatic-malar area. Palliative surgery was performed to maintain her residual vision and to reduce the pain caused by the compression of local structures. Because of the limited access of autologous skin grafts in pediatric patients with XP who are severely affected, we opted to use an acellular dermal matrix. There was 100% graft uptake, and the pain due to compression by the tumor was alleviated. This case demonstrates that acellular dermal matrices can be safely and effectively used in oncological facial reconstruction, especially in patients with progressive conditions such as XP.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001442
spellingShingle Kamlen Pillay, MBChB
Saleigh Adams, MBChB, FC Plast Surg
Laura Vandermaesen, MD
Donald Anthony Hudson, MBChB, MMed, FRCS
Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
Plastic and Reconstructive Surgery, Global Open
title Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_full Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_fullStr Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_full_unstemmed Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_short Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_sort acellular dermal matrix treating periocular melanoma in a patient with xeroderma pigmentosa
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001442
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