A Toxoplasma gondii lipoxygenase-like enzyme is necessary for virulence and changes localization associated with the host immune response

A Toxoplasma gondii lipoxygenase-like enzyme is necessary for virulence and changes localization associated with the host immune response

ABSTRACT While the asexual cycle of Toxoplasma gondii can occur in any warm-blooded animal, the sexual cycle is restricted to the feline intestine. We previously determined that because cats lack delta-6-desaturase activity in their intestines, they build up excess linoleic acid, which signals T. go...

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Bibliographic Details
Main Authors: Carlos J. Ramírez-Flores, Billy Joel Erazo Flores, Andrés M. Tibabuzo Perdomo, Katie L. Barnes, Sarah K. Wilson, Carolina Mendoza Cavazos, Laura J. Knoll
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
immune response
leukocytes
lipoxygenase
cytokines
Toxoplasma gondii
Online Access:https://journals.asm.org/doi/10.1128/mbio.01279-23

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