Ultrasensitive Determination of Glial-Fibrillary-Acidic-Protein (GFAP) in Human Serum-Matrix with a Label-Free Impedimetric Immunosensor

Ultrasensitive Determination of Glial-Fibrillary-Acidic-Protein (GFAP) in Human Serum-Matrix with a Label-Free Impedimetric Immunosensor

In this work, immobilizing anti-GFAP antibodies via covalent attachment onto L-cysteine/gold nanoparticles that were modified with screen-printed carbon electrodes (Anti-GFAP/L-cys/AuNps/SPCE) resulted in the development of a sensitive label-free impedance immunosensor for the detection of Glial Fib...

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Bibliographic Details
Main Authors: Goksu Ozcelikay, Fariba Mollarasouli, Mehmet Altay Unal, Kıvılcım Gucuyener, Sibel A. Ozkan
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biosensors
Subjects:
label-free impedance immunosensor
screen printed carbon electrode (SPCE)
Au nanoparticles (Au NPs)
glial fibrillary acidic protein (GFAP)
Online Access:https://www.mdpi.com/2079-6374/12/12/1165

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