Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum.

Inflammasome is an intracellular protein complex that serves as cytosolic pattern recognition receptor (PRR) to engage with pathogens and to process cytokines of the interleukin-1 (IL-1) family into bioactive molecules. It has been established that interleukin-1β (IL-1β) is important to host defense...

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Bibliographic Details
Main Authors: Tzu-Hsuan Chang, Juin-Hua Huang, Hsiu-Chao Lin, Wen-Yu Chen, Yu-Hsiang Lee, Li-Chung Hsu, Mihai G Netea, Jenny P-Y Ting, Betty A Wu-Hsieh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5510910?pdf=render

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