The Expression Regulation and Biological Function of Autotaxin

The Expression Regulation and Biological Function of Autotaxin

Autotaxin (ATX) is a secreted glycoprotein and functions as a key enzyme to produce extracellular lysophosphatidic acid (LPA). LPA interacts with at least six G protein-coupled receptors, LPAR1-6, on the cell membrane to activate various signal transduction pathways through distinct G proteins, such...

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Bibliographic Details
Main Authors:	Xiaotian Zhang, Mengmiao Li, Nan Yin, Junjie Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Cells
Subjects:	Autotaxin (ATX) lysophosphatidic acid (LPA) ATX-LPA axis cancer
Online Access:	https://www.mdpi.com/2073-4409/10/4/939

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