PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses.

PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses.

Poly (ADP-ribose) polymerases (PARPs) catalyze the transfer of multiple poly(ADP-ribose) units onto target proteins. Poly(ADP-ribosyl)ation plays a crucial role in a variety of cellular processes including, most prominently, auto-activation of PARP at sites of DNA breaks to activate DNA repair proce...

Full description

Bibliographic Details
Main Authors:	Junqi Song, Brian D Keppler, Robert R Wise, Andrew F Bent
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-05-01
Series:	PLoS Genetics
Online Access:	http://europepmc.org/articles/PMC4423837?pdf=render

Similar Items

New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage
by: Zongying Gu, et al.
Published: (2019-08-01)

Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy
by: Stephen A. Jannetti, et al.
Published: (2020-03-01)

The Promise of Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Gliomas
by: Nazanin Majd, et al.
Published: (2020-11-01)

Poly-ADP-ribose polymerase (PARP) inhibitors and ovarian function
by: Jiajia Li, et al.
Published: (2023-01-01)

Poly(ADP-ribose) polymerase (PARP) inhibitors and ovarian cancer
by: Chia-Hao Liu, et al.
Published: (2017-10-01)

Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery
by: Fernet Marie, et al.
Published: (2003-07-01)

Recognition of Platinum−DNA Damage by Poly(ADP-ribose) Polymerase-1
by: Zhu, Guangyu, et al.
Published: (2011)

Clinical Application of Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Prostate Cancer
by: Andrisha-Jade Inderjeeth, et al.
Published: (2022-11-01)

Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes
by: Sarkar Oli, et al.
Published: (2009-12-01)

Methods for Purification of Proteins Associated with Cellular Poly(ADP-Ribose) and PARP-Specific Poly(ADP-Ribose)
by: Rood, Jennifer E., et al.
Published: (2014)

Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) – Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy
by: Daniel Harrision, et al.
Published: (2020-08-01)

Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors
by: Isabella Faraoni, et al.
Published: (2018-12-01)

Targeted therapy with Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of solid tumours
by: Faustyna Piędel, et al.
Published: (2020-03-01)

Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1)
by: Zhimin Zhang, et al.
Published: (2020-01-01)

The Inhibition and Treatment of Breast Cancer with Poly (ADP-ribose) Polymerase (PARP-1) Inhibitors
by: Joseph A. De Soto, Xianyan Wang, Yohei Tominaga, Rui-Hong Wang, Liu Cao, Wenhui Qiao, Cuiling Li, Xiaoling Xu, Amanda P. Skoumbourdis, Sheila A. Prindiville, Craig J. Thomas, Chu-Xia Deng
Published: (2006-01-01)

Synthesis and study of new 4-quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP)
by: Gyozo Kulcsar, et al.
Published: (2003-06-01)

The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.
by: Arnaud J Legrand, et al.
Published: (2013-01-01)

Associations with response to Poly(ADP-ribose) Polymerase (PARP) inhibitors in patients with metastatic breast cancer
by: A. Desnoyers, et al.
Published: (2022-03-01)

The Antiviral Activities of Poly-ADP-Ribose Polymerases
by: Mathilde Malgras, et al.
Published: (2021-03-01)

Beyond PARP1: The Potential of Other Members of the Poly (ADP-Ribose) Polymerase Family in DNA Repair and Cancer Therapeutics
by: Iain A. Richard, et al.
Published: (2022-01-01)

Copy number analyses of DNA repair genes reveal the role of poly(ADP-ribose) polymerase (PARP) in tree longevity
by: Yuta Aoyagi Blue, et al.
Published: (2021-07-01)

Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage
by: Masato Mashimo, et al.
Published: (2022-07-01)

Increased DNA damage in progression of COPD: a response by poly(ADP-ribose) polymerase-1.
by: Ingrid Oit-Wiscombe, et al.
Published: (2013-01-01)

Active Targeted Nanoparticles for Delivery of Poly(ADP-ribose) Polymerase (PARP) Inhibitors: A Preliminary Review
by: Saman Sargazi, et al.
Published: (2021-09-01)

DNA Repair Enzyme Poly(ADP-Ribose) Polymerase 1/2 (PARP1/2)-Targeted Nuclear Imaging and Radiotherapy
by: Nghia T. Nguyen, et al.
Published: (2022-02-01)

Fused in Sarcoma (FUS) in DNA Repair: Tango with Poly(ADP-ribose) Polymerase 1 and Compartmentalisation of Damaged DNA
by: Maria V. Sukhanova, et al.
Published: (2020-09-01)

Combined Strategies with Poly (ADP-Ribose) Polymerase (PARP) Inhibitors for the Treatment of Ovarian Cancer: A Literature Review
by: Stergios Boussios, et al.
Published: (2019-08-01)

Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer.
by: Yufeng Wang, et al.
Published: (2014-01-01)

Inhibition of Poly ADP-Ribose Glycohydrolase Sensitizes Ovarian Cancer Cells to Poly ADP-Ribose Polymerase Inhibitors and Platinum Agents
by: Emad Matanes, et al.
Published: (2021-10-01)

Poly ADP-ribose polymerase-1: an international molecule of mystery.
by: Woodhouse, B, et al.
Published: (2008)

Family-wide analysis of poly(ADP-ribose) polymerase activity
by: Vyas, Sejal, et al.
Published: (2015)

Poly (ADP-ribose) polymerase inhibitors in the management of ovarian cancer
by: Maurie Markman
Published: (2018-01-01)

The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy
by: M. Javle, et al.
Published: (2011-11-01)

Selection of potential natural compounds for poly-ADP-ribose polymerase (PARP) inhibition in glioblastoma therapy by in silico screening methods
by: Arunraj Tharamelveliyil Rajendran, et al.
Published: (2023-07-01)

Transient HSP90 inhibition enhances the sensitivity of mantle cell lymphoma to poly (ADP-ribose) polymerase (PARP) inhibitors
by: Chaowen Shi, et al.
Published: (2023-09-01)

Poly ADP-ribose polymerase (PARP) inhibitors - new therapeutic strategies in Acute Myeloid Leukemia: a literature review
by: Emilia Nowicka, et al.
Published: (2022-12-01)

Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer’s Disease
by: Felipe Salech, et al.
Published: (2020-08-01)

Use of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinic
by: Aniello Cerrato, et al.
Published: (2016-11-01)

Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells
by: Junji Xing, et al.
Published: (2021-05-01)

Poly(ADP-ribose) polymerase 1 (PARP1) overexpression in human breast cancer stem cells and resistance to olaparib.
by: Marine Gilabert, et al.
Published: (2014-01-01)