The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature Review
Late diagnosis and treatment of septic arthritis (SA) after anterior cruciate ligament reconstruction (ACL-R) can lead to graft and cartilage damage. Pathogen eradication time may be the key to preventing the development of osteoarthritis. The purpose of this study was to evaluate the effect of the...
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MDPI AG
2022-11-01
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| Online Access: | https://www.mdpi.com/2076-3417/12/22/11679 |
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| author | Michał Waszczykowski Anna Fabiś-Strobin Agnieszka Korczyc-Stępnicka Krzysztof Małecki Jerzy Białecki Paweł Bartosz Jarosław Fabiś |
| author_facet | Michał Waszczykowski Anna Fabiś-Strobin Agnieszka Korczyc-Stępnicka Krzysztof Małecki Jerzy Białecki Paweł Bartosz Jarosław Fabiś |
| author_sort | Michał Waszczykowski |
| collection | DOAJ |
| description | Late diagnosis and treatment of septic arthritis (SA) after anterior cruciate ligament reconstruction (ACL-R) can lead to graft and cartilage damage. Pathogen eradication time may be the key to preventing the development of osteoarthritis. The purpose of this study was to evaluate the effect of the proposed management of SA after ACL-R on knee function, pathogen eradication time and knee cartilage status on MRI. Five patients with acute knee SA after ACL-R were included in this study. All five patients underwent knee arthroscopic debridement with lavage and flow drainage with physiological saline with vancomycin. All five patients underwent clinical assessment, isokinetic examinations and MRI quantitative cartilage thickness evaluation at two follow-up points: at a mean of 10.9 years and at a mean of 18.1 years. Slight statistical differences in cartilage thickness on the medial femoral condyle were observed between the SA and control groups (2.077 mm and 2.237 mm, respectively; <i>p</i> = 0.021). There were no significant differences in cartilage thickness between the first and last follow-ups in the SA knees. The proposed treatment could lead to a faster eradication of infection, and thus protect against the early development of osteoarthritis. The quadriceps peak torque deficit may persist afterwards at a mean of 18.1 years follow-up. |
| first_indexed | 2024-03-09T18:29:01Z |
| format | Article |
| id | doaj.art-1b1d69c1e28640b5a390ba60661b99b1 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T18:29:01Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-1b1d69c1e28640b5a390ba60661b99b12023-11-24T07:39:09ZengMDPI AGApplied Sciences2076-34172022-11-0112221167910.3390/app122211679The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature ReviewMichał Waszczykowski0Anna Fabiś-Strobin1Agnieszka Korczyc-Stępnicka2Krzysztof Małecki3Jerzy Białecki4Paweł Bartosz5Jarosław Fabiś6Department of Arthroscopy, Minimally Invasive Surgery and Sports Traumatology, Chair of Orthopaedics, Traumatology and Rehabilitation, Medical University of Lodz, Kosciuszki 4, 90-419 Lodz, PolandClinic of Orthopaedic and Traumatology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, PolandFMC Medical Center, Kopernika 48/50, 90-553 Lodz, PolandClinic of Orthopaedic and Traumatology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, PolandOrthopedic Department, Centre of Postgraduate Medical Education, Konarskiego 13, Kosciuszki 3/10B, 05-400 Otwock, PolandOrthopedic Department, Centre of Postgraduate Medical Education, Konarskiego 13, Kosciuszki 3/10B, 05-400 Otwock, PolandDepartment of Arthroscopy, Minimally Invasive Surgery and Sports Traumatology, Chair of Orthopaedics, Traumatology and Rehabilitation, Medical University of Lodz, Kosciuszki 4, 90-419 Lodz, PolandLate diagnosis and treatment of septic arthritis (SA) after anterior cruciate ligament reconstruction (ACL-R) can lead to graft and cartilage damage. Pathogen eradication time may be the key to preventing the development of osteoarthritis. The purpose of this study was to evaluate the effect of the proposed management of SA after ACL-R on knee function, pathogen eradication time and knee cartilage status on MRI. Five patients with acute knee SA after ACL-R were included in this study. All five patients underwent knee arthroscopic debridement with lavage and flow drainage with physiological saline with vancomycin. All five patients underwent clinical assessment, isokinetic examinations and MRI quantitative cartilage thickness evaluation at two follow-up points: at a mean of 10.9 years and at a mean of 18.1 years. Slight statistical differences in cartilage thickness on the medial femoral condyle were observed between the SA and control groups (2.077 mm and 2.237 mm, respectively; <i>p</i> = 0.021). There were no significant differences in cartilage thickness between the first and last follow-ups in the SA knees. The proposed treatment could lead to a faster eradication of infection, and thus protect against the early development of osteoarthritis. The quadriceps peak torque deficit may persist afterwards at a mean of 18.1 years follow-up.https://www.mdpi.com/2076-3417/12/22/11679septic arthritiskneeanterior cruciate ligamentreconstructionosteoarthritisisokinetic evaluation |
| spellingShingle | Michał Waszczykowski Anna Fabiś-Strobin Agnieszka Korczyc-Stępnicka Krzysztof Małecki Jerzy Białecki Paweł Bartosz Jarosław Fabiś The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature Review Applied Sciences septic arthritis knee anterior cruciate ligament reconstruction osteoarthritis isokinetic evaluation |
| title | The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature Review |
| title_full | The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature Review |
| title_fullStr | The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature Review |
| title_full_unstemmed | The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature Review |
| title_short | The Speed of Pathogen Eradication May Prevent the Early Development of Cartilage Destruction: Case Series of Long-Term Follow-Up of Septic Arthritis (SA) after Anterior Cruciate Ligament Reconstruction (ACL-R) and Literature Review |
| title_sort | speed of pathogen eradication may prevent the early development of cartilage destruction case series of long term follow up of septic arthritis sa after anterior cruciate ligament reconstruction acl r and literature review |
| topic | septic arthritis knee anterior cruciate ligament reconstruction osteoarthritis isokinetic evaluation |
| url | https://www.mdpi.com/2076-3417/12/22/11679 |
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