Mining the 3′UTR of Autism-implicated Genes for SNPs Perturbing MicroRNA Regulation

Mining the 3′UTR of Autism-implicated Genes for SNPs Perturbing MicroRNA Regulation

Autism spectrum disorder (ASD) refers to a group of childhood neurodevelopmental disorders with polygenic etiology. The expression of many genes implicated in ASD is tightly regulated by various factors including microRNAs (miRNAs), a class of noncoding RNAs ∼22 nucleotides in length that function t...

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Bibliographic Details
Main Authors: Varadharajan Vaishnavi, Mayakannan Manikandan, Arasambattu Kannan Munirajan
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Autism spectrum disorder
MicroRNA
Single nucleotide polymorphism
3′UTR-SNP
Gene regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022914000242

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