Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome
A longitudinal study was performed with sera and urine of patients with acquired immune deficiency syndrome (AIDS), taken before, during and after clinically Toxoplasma infection. The tested patients were followed for an average of two years. The titres of the specific IgG and IgM antibodies were me...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
1997-09-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761997000500005 |
| _version_ | 1797756690220711936 |
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| author | Alberto Fachado Lisset Fonseca Luis Fonte Esteban Alberti Raymundo Cox Frank Bandera |
| author_facet | Alberto Fachado Lisset Fonseca Luis Fonte Esteban Alberti Raymundo Cox Frank Bandera |
| author_sort | Alberto Fachado |
| collection | DOAJ |
| description | A longitudinal study was performed with sera and urine of patients with acquired immune deficiency syndrome (AIDS), taken before, during and after clinically Toxoplasma infection. The tested patients were followed for an average of two years. The titres of the specific IgG and IgM antibodies were measured by an indirect fluorescent antibody test (IFAT), and the appearance of circulating antigens of T. gondii was determined in 36 urine samples of 13 patients with neurotoxoplasmosis by means of the coagglutination test. The presence of T. gondii antigens in the urine of AIDS patients by this test was correlated with the immunoblot technique, with clinical symptoms and also with pathological findings. Our results indicate that the detection of T. gondii antigens in the urine of AIDS patients can be regarded as a rapid and efficient method for the diagnosis of acute toxoplasmosis |
| first_indexed | 2024-03-12T18:05:08Z |
| format | Article |
| id | doaj.art-1b21d69b4e044446a4d15ba2f17583ed |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:05:08Z |
| publishDate | 1997-09-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-1b21d69b4e044446a4d15ba2f17583ed2023-08-02T09:28:29ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601997-09-0192558910.1590/S0074-02761997000500005Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency SyndromeAlberto FachadoLisset FonsecaLuis FonteEsteban AlbertiRaymundo CoxFrank BanderaA longitudinal study was performed with sera and urine of patients with acquired immune deficiency syndrome (AIDS), taken before, during and after clinically Toxoplasma infection. The tested patients were followed for an average of two years. The titres of the specific IgG and IgM antibodies were measured by an indirect fluorescent antibody test (IFAT), and the appearance of circulating antigens of T. gondii was determined in 36 urine samples of 13 patients with neurotoxoplasmosis by means of the coagglutination test. The presence of T. gondii antigens in the urine of AIDS patients by this test was correlated with the immunoblot technique, with clinical symptoms and also with pathological findings. Our results indicate that the detection of T. gondii antigens in the urine of AIDS patients can be regarded as a rapid and efficient method for the diagnosis of acute toxoplasmosishttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761997000500005Toxoplasma gondii antigenscoagglutination testAIDS patientsneurotoxoplasmosis |
| spellingShingle | Alberto Fachado Lisset Fonseca Luis Fonte Esteban Alberti Raymundo Cox Frank Bandera Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome Memorias do Instituto Oswaldo Cruz Toxoplasma gondii antigens coagglutination test AIDS patients neurotoxoplasmosis |
| title | Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome |
| title_full | Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome |
| title_fullStr | Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome |
| title_full_unstemmed | Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome |
| title_short | Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome |
| title_sort | toxoplasma gondii antigenuria in patients with acquired immune deficiency syndrome |
| topic | Toxoplasma gondii antigens coagglutination test AIDS patients neurotoxoplasmosis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761997000500005 |
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