Tissue xanthine oxidoreductase activity in a mouse model of aristolochic acid nephropathy

Tissue xanthine oxidoreductase activity in a mouse model of aristolochic acid nephropathy

Xanthine oxidoreductase (XOR) is a critical enzyme in purine metabolism and uric acid production, and its levels are reported to increase during stress, thereby promoting organ damage. Herein, we investigated the activity of XOR in a mouse model of aristolochic acid I (AA)‐induced nephropathy, a typ...

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Bibliographic Details
Main Authors: Takeo Ishii, Tomohiro Kumagae, Hiromichi Wakui, Shingo Urate, Shohei Tanaka, Eriko Abe, Toru Suzuki, Takahiro Yamaji, Sho Kinguchi, Ryu Kobayashi, Kotaro Haruhara, Takashi Nakamura, Shuzo Kobayashi, Kouichi Tamura
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:FEBS Open Bio
Subjects:
aristolochic acid
mouse model
nephropathy
xanthine oxidoreductase
Online Access:https://doi.org/10.1002/2211-5463.13083

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