J Proteins Counteract Amyloid Propagation and Toxicity in Yeast
The accumulation of misfolded proteins as amyloids is associated with pathology in dozens of debilitating human disorders, including diabetes, Alzheimer’s, Parkinson’s, and Huntington’s diseases. Expressing human amyloid-forming proteins in yeast is toxic, and yeast prions that propagate as infectio...
Main Authors: | Daniel C. Masison, Michael Reidy, Jyotsna Kumar |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
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Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/11/9/1292 |
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