Histoid leprosy in the era of elimination

Histoid leprosy is a variant of Lepromatous leprosy believed to occur due to a mutant strain of leprosy bacillus called as Histoid Bacillus. It was first described by Wade in 1960 in patients from Phillipines. It occurs in patients relapsing after Dapsone monotherapy, in the presence of Dapsone resi...

Full description

Bibliographic Details
Main Authors: Sukumar Dandekeri, Hyacinth Peter Pinto, Ramesh M Bhat, M K Srinath
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Muller Journal of Medical Sciences and Research
Subjects:
Online Access:http://www.mjmsr.net/article.asp?issn=0975-9727;year=2013;volume=4;issue=1;spage=29;epage=31;aulast=Dandekeri
_version_ 1811319449659113472
author Sukumar Dandekeri
Hyacinth Peter Pinto
Ramesh M Bhat
M K Srinath
author_facet Sukumar Dandekeri
Hyacinth Peter Pinto
Ramesh M Bhat
M K Srinath
author_sort Sukumar Dandekeri
collection DOAJ
description Histoid leprosy is a variant of Lepromatous leprosy believed to occur due to a mutant strain of leprosy bacillus called as Histoid Bacillus. It was first described by Wade in 1960 in patients from Phillipines. It occurs in patients relapsing after Dapsone monotherapy, in the presence of Dapsone resistance or at times denovo, presenting with lesions mainly over bony prominences. Herein, we present a case of a 37 year old male who presented with skin coloured raised lesions mainly over the trunk, chest, neck and ears in contrast to its usual site of presentation, associated with tingling sensation over the hands and feet. A histopathological examination of the skin lesion was ordered which revealed sheets of histiocytes and lepra bacilli on hematoxylin and eosin and acid fast staining. On correlating the clinical and histopathological findings we came to a diagnosis of Histoid leprosy. The patient was promptly treated with MB-MDT and followed up.
first_indexed 2024-04-13T12:42:28Z
format Article
id doaj.art-1b2de74a4f4b4ea79416d18e9c08555b
institution Directory Open Access Journal
issn 0975-9727
language English
last_indexed 2024-04-13T12:42:28Z
publishDate 2013-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Muller Journal of Medical Sciences and Research
spelling doaj.art-1b2de74a4f4b4ea79416d18e9c08555b2022-12-22T02:46:28ZengWolters Kluwer Medknow PublicationsMuller Journal of Medical Sciences and Research0975-97272013-01-0141293110.4103/0975-9727.112275Histoid leprosy in the era of eliminationSukumar DandekeriHyacinth Peter PintoRamesh M BhatM K SrinathHistoid leprosy is a variant of Lepromatous leprosy believed to occur due to a mutant strain of leprosy bacillus called as Histoid Bacillus. It was first described by Wade in 1960 in patients from Phillipines. It occurs in patients relapsing after Dapsone monotherapy, in the presence of Dapsone resistance or at times denovo, presenting with lesions mainly over bony prominences. Herein, we present a case of a 37 year old male who presented with skin coloured raised lesions mainly over the trunk, chest, neck and ears in contrast to its usual site of presentation, associated with tingling sensation over the hands and feet. A histopathological examination of the skin lesion was ordered which revealed sheets of histiocytes and lepra bacilli on hematoxylin and eosin and acid fast staining. On correlating the clinical and histopathological findings we came to a diagnosis of Histoid leprosy. The patient was promptly treated with MB-MDT and followed up.http://www.mjmsr.net/article.asp?issn=0975-9727;year=2013;volume=4;issue=1;spage=29;epage=31;aulast=DandekeriMultibacillary multidrug therapyElimination
spellingShingle Sukumar Dandekeri
Hyacinth Peter Pinto
Ramesh M Bhat
M K Srinath
Histoid leprosy in the era of elimination
Muller Journal of Medical Sciences and Research
Multibacillary multidrug therapy
Elimination
title Histoid leprosy in the era of elimination
title_full Histoid leprosy in the era of elimination
title_fullStr Histoid leprosy in the era of elimination
title_full_unstemmed Histoid leprosy in the era of elimination
title_short Histoid leprosy in the era of elimination
title_sort histoid leprosy in the era of elimination
topic Multibacillary multidrug therapy
Elimination
url http://www.mjmsr.net/article.asp?issn=0975-9727;year=2013;volume=4;issue=1;spage=29;epage=31;aulast=Dandekeri
work_keys_str_mv AT sukumardandekeri histoidleprosyintheeraofelimination
AT hyacinthpeterpinto histoidleprosyintheeraofelimination
AT rameshmbhat histoidleprosyintheeraofelimination
AT mksrinath histoidleprosyintheeraofelimination