Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine

Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine

Abstract Background A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium falciparum isolates, 11 years after CQ withdrawal in Southeast Niger...

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Bibliographic Details
Main Authors: Moses N. Ikegbunam, Charles N. Nkonganyi, Bolaji N. Thomas, Charles O. Esimone, Thirumalaisamy P. Velavan, Olusola Ojurongbe
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Drug resistance
Chloroquine
Pfmdr1
Pfcrt
Online Access:http://link.springer.com/article/10.1186/s12936-019-2977-6

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