Thymic Neuroblastoma within a Thymic Cyst in an Adult
Case Presentation: A 65-year-old female patient with no clinical manifestations was hospitalized for examination and treatment of an anterior mediastinal tumor found at the time of a regular health checkup. Enhanced computed tomography (CT) and magnetic resonance imaging revealed a cystic lesion con...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2012-08-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/342357 |
| _version_ | 1817999527462830080 |
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| author | Yuichiro Ueda Mitsugu Omasa Toshihiko Taki Ryo Okabe Hiroyuki Cho Tsuyoshi Shoji Cheng-long Huang Yoshiaki Yuba |
| author_facet | Yuichiro Ueda Mitsugu Omasa Toshihiko Taki Ryo Okabe Hiroyuki Cho Tsuyoshi Shoji Cheng-long Huang Yoshiaki Yuba |
| author_sort | Yuichiro Ueda |
| collection | DOAJ |
| description | Case Presentation: A 65-year-old female patient with no clinical manifestations was hospitalized for examination and treatment of an anterior mediastinal tumor found at the time of a regular health checkup. Enhanced computed tomography (CT) and magnetic resonance imaging revealed a cystic lesion containing a solid tumor. Positron emission tomography-CT demonstrated increased uptake in the solid lesion. Tumor resection with total thymectomy was performed. A pathological diagnosis of thymic neuroblastoma within a thymic cyst was made. Micorscopic examination revealed that tumor cells of the solid component were lined with thymic epithelial cells of the inner cyst wall. Furthermore, some tumor cells of the solid component had melanin granules. These findings suggest that this tumor arose from progenitors of the thymic epithelial cells with the potential to differentiate along neural lines. Conclusions: Neuroblastoma commonly occurs in children. However, the diagnosis of neuroblastoma in adults has been reported in several case reports. We report an adult case of histogenetically informative thymic neuroblastoma within a thymic cyst. There are no standard treatment strategies and chemotherapy protocols. Complete surgical resection might be important for a better outcome. |
| first_indexed | 2024-04-14T03:10:02Z |
| format | Article |
| id | doaj.art-1b31774332bc475bacd17cf89086d942 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-04-14T03:10:02Z |
| publishDate | 2012-08-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-1b31774332bc475bacd17cf89086d9422022-12-22T02:15:37ZengKarger PublishersCase Reports in Oncology1662-65752012-08-015245946310.1159/000342357342357Thymic Neuroblastoma within a Thymic Cyst in an AdultYuichiro UedaMitsugu OmasaToshihiko TakiRyo OkabeHiroyuki ChoTsuyoshi ShojiCheng-long HuangYoshiaki YubaCase Presentation: A 65-year-old female patient with no clinical manifestations was hospitalized for examination and treatment of an anterior mediastinal tumor found at the time of a regular health checkup. Enhanced computed tomography (CT) and magnetic resonance imaging revealed a cystic lesion containing a solid tumor. Positron emission tomography-CT demonstrated increased uptake in the solid lesion. Tumor resection with total thymectomy was performed. A pathological diagnosis of thymic neuroblastoma within a thymic cyst was made. Micorscopic examination revealed that tumor cells of the solid component were lined with thymic epithelial cells of the inner cyst wall. Furthermore, some tumor cells of the solid component had melanin granules. These findings suggest that this tumor arose from progenitors of the thymic epithelial cells with the potential to differentiate along neural lines. Conclusions: Neuroblastoma commonly occurs in children. However, the diagnosis of neuroblastoma in adults has been reported in several case reports. We report an adult case of histogenetically informative thymic neuroblastoma within a thymic cyst. There are no standard treatment strategies and chemotherapy protocols. Complete surgical resection might be important for a better outcome.http://www.karger.com/Article/FullText/342357Thymic neuroblastomaThymic cystAdult |
| spellingShingle | Yuichiro Ueda Mitsugu Omasa Toshihiko Taki Ryo Okabe Hiroyuki Cho Tsuyoshi Shoji Cheng-long Huang Yoshiaki Yuba Thymic Neuroblastoma within a Thymic Cyst in an Adult Case Reports in Oncology Thymic neuroblastoma Thymic cyst Adult |
| title | Thymic Neuroblastoma within a Thymic Cyst in an Adult |
| title_full | Thymic Neuroblastoma within a Thymic Cyst in an Adult |
| title_fullStr | Thymic Neuroblastoma within a Thymic Cyst in an Adult |
| title_full_unstemmed | Thymic Neuroblastoma within a Thymic Cyst in an Adult |
| title_short | Thymic Neuroblastoma within a Thymic Cyst in an Adult |
| title_sort | thymic neuroblastoma within a thymic cyst in an adult |
| topic | Thymic neuroblastoma Thymic cyst Adult |
| url | http://www.karger.com/Article/FullText/342357 |
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