The <i>Neisseria gonorrhoeae</i> Vaccine Candidate NHBA Elicits Antibodies That Are Bactericidal, Opsonophagocytic and That Reduce Gonococcal Adherence to Epithelial Cells

The <i>Neisseria gonorrhoeae</i> Vaccine Candidate NHBA Elicits Antibodies That Are Bactericidal, Opsonophagocytic and That Reduce Gonococcal Adherence to Epithelial Cells

Due to the continuing emergence of multidrug resistant strains of <i>Neisseria gonorrhoeae</i> there is an urgent need for the development of a gonococcal vaccine. We evaluated the gonococcal <i>Neisseria</i> heparin binding antigen (NHBA) as a potential vaccine candidate, in...

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Bibliographic Details
Main Authors: Evgeny A. Semchenko, Christopher J. Day, Kate L. Seib
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
<i>Neisseria gonorrhoeae</i>
gonococcus
<i>Neisseria</i> heparin binding antigen (NHBA)
bactericidal activity
opsonophagocytic activity
infection blocking
Online Access:https://www.mdpi.com/2076-393X/8/2/219

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