Evaluation of Different Doses in Inhaled Therapy: A Comprehensive Analysis
Background. Currently, there is a considerable degree of confusion over the dosage of inhaled medications. Here, we carried out a review of all the doses used for the devices used in inhalation therapy. Methods. We first performed a systematic search of the different inhalation devices included on t...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-08-01
|
| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/15/9/2206 |
| _version_ | 1827724459133370368 |
|---|---|
| author | José Luis Lopez-Campos Rocio Reinoso-Arija Marta Ferrer Galván Auxiliadora Romero Falcón Francisco J. Alvarez-Gutiérrez Francisco Ortega-Ruiz Esther Quintana-Gallego |
| author_facet | José Luis Lopez-Campos Rocio Reinoso-Arija Marta Ferrer Galván Auxiliadora Romero Falcón Francisco J. Alvarez-Gutiérrez Francisco Ortega-Ruiz Esther Quintana-Gallego |
| author_sort | José Luis Lopez-Campos |
| collection | DOAJ |
| description | Background. Currently, there is a considerable degree of confusion over the dosage of inhaled medications. Here, we carried out a review of all the doses used for the devices used in inhalation therapy. Methods. We first performed a systematic search of the different inhalation devices included on the July 2023 Spanish Ministry of Health Billing List. We then consulted the Spanish Agency for Medicines and Health Products to find the updated official label and to obtain the information on the exact composition. Results. We identified 90 unique products, of which 22 were long-acting bronchodilators (and combinations thereof) and 68 were products containing inhaled corticosteroids (ICS). Overall, 10 products with bronchodilators and 40 with ICS were marketed with the metered dose, while 11 with bronchodilators and 28 with ICS were marketed with the delivered dose. In addition, in some bronchodilators, the drug was referred to as a type of salt, whereas in others the information referred to the drug itself. Conclusions. Our data show that for each inhaled drug there may be up to four different doses and that the marketed name may refer to any of these. Clinicians must be aware of these different dosages when prescribing inhaled medications. |
| first_indexed | 2024-03-10T22:16:05Z |
| format | Article |
| id | doaj.art-1b3357db61ae430c8f50bf6e052dd45a |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-10T22:16:05Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-1b3357db61ae430c8f50bf6e052dd45a2023-11-19T12:26:28ZengMDPI AGPharmaceutics1999-49232023-08-01159220610.3390/pharmaceutics15092206Evaluation of Different Doses in Inhaled Therapy: A Comprehensive AnalysisJosé Luis Lopez-Campos0Rocio Reinoso-Arija1Marta Ferrer Galván2Auxiliadora Romero Falcón3Francisco J. Alvarez-Gutiérrez4Francisco Ortega-Ruiz5Esther Quintana-Gallego6Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, SpainUnidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, SpainUnidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, SpainUnidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, SpainUnidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, SpainUnidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, SpainUnidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, 41013 Seville, SpainBackground. Currently, there is a considerable degree of confusion over the dosage of inhaled medications. Here, we carried out a review of all the doses used for the devices used in inhalation therapy. Methods. We first performed a systematic search of the different inhalation devices included on the July 2023 Spanish Ministry of Health Billing List. We then consulted the Spanish Agency for Medicines and Health Products to find the updated official label and to obtain the information on the exact composition. Results. We identified 90 unique products, of which 22 were long-acting bronchodilators (and combinations thereof) and 68 were products containing inhaled corticosteroids (ICS). Overall, 10 products with bronchodilators and 40 with ICS were marketed with the metered dose, while 11 with bronchodilators and 28 with ICS were marketed with the delivered dose. In addition, in some bronchodilators, the drug was referred to as a type of salt, whereas in others the information referred to the drug itself. Conclusions. Our data show that for each inhaled drug there may be up to four different doses and that the marketed name may refer to any of these. Clinicians must be aware of these different dosages when prescribing inhaled medications.https://www.mdpi.com/1999-4923/15/9/2206inhaled drugsCOPDasthmadoseinhalers |
| spellingShingle | José Luis Lopez-Campos Rocio Reinoso-Arija Marta Ferrer Galván Auxiliadora Romero Falcón Francisco J. Alvarez-Gutiérrez Francisco Ortega-Ruiz Esther Quintana-Gallego Evaluation of Different Doses in Inhaled Therapy: A Comprehensive Analysis Pharmaceutics inhaled drugs COPD asthma dose inhalers |
| title | Evaluation of Different Doses in Inhaled Therapy: A Comprehensive Analysis |
| title_full | Evaluation of Different Doses in Inhaled Therapy: A Comprehensive Analysis |
| title_fullStr | Evaluation of Different Doses in Inhaled Therapy: A Comprehensive Analysis |
| title_full_unstemmed | Evaluation of Different Doses in Inhaled Therapy: A Comprehensive Analysis |
| title_short | Evaluation of Different Doses in Inhaled Therapy: A Comprehensive Analysis |
| title_sort | evaluation of different doses in inhaled therapy a comprehensive analysis |
| topic | inhaled drugs COPD asthma dose inhalers |
| url | https://www.mdpi.com/1999-4923/15/9/2206 |
| work_keys_str_mv | AT joseluislopezcampos evaluationofdifferentdosesininhaledtherapyacomprehensiveanalysis AT rocioreinosoarija evaluationofdifferentdosesininhaledtherapyacomprehensiveanalysis AT martaferrergalvan evaluationofdifferentdosesininhaledtherapyacomprehensiveanalysis AT auxiliadoraromerofalcon evaluationofdifferentdosesininhaledtherapyacomprehensiveanalysis AT franciscojalvarezgutierrez evaluationofdifferentdosesininhaledtherapyacomprehensiveanalysis AT franciscoortegaruiz evaluationofdifferentdosesininhaledtherapyacomprehensiveanalysis AT estherquintanagallego evaluationofdifferentdosesininhaledtherapyacomprehensiveanalysis |