Evaluation of the genotoxicity and mutagenicity of isoeleutherin and eleutherin isolated from Eleutherine plicata herb. using bioassays and in silico approaches

Evaluation of the genotoxicity and mutagenicity of isoeleutherin and eleutherin isolated from Eleutherine plicata herb. using bioassays and in silico approaches

The biological activities of Eleutherine plicata Herb. have been linked to isoeleutherin and eleutherin naphthoquinones. However, there are few reports in the literature regarding the cytotoxic and genotoxic potential of these compounds. There are reports in the literature that the inhibition of top...

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Bibliographic Details
Main Authors:	Ana Laura Gadelha Castro, Jorddy Neves Cruz, Daniele Ferreira Sodré, Juliana Correa-Barbosa, Rufine Azonsivo, Mozaniel Santana de Oliveira, José Edson de Sousa Siqueira, Natasha Costa da Rocha Galucio, Marcelo de Oliveira Bahia, Rommel Mario Rodriguez Burbano, Andrey Moacir do Rosário Marinho, Sandro Percário, Maria Fâni Dolabela, Valdicley Vieira Vale
Format:	Article
Language:	English
Published:	Elsevier 2021-04-01
Series:	Arabian Journal of Chemistry
Subjects:	Genotoxicity Mutagenicity Naphthoquinones
Online Access:	http://www.sciencedirect.com/science/article/pii/S187853522100099X

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