BMPR2 mutation and clinical response to imatinib in a case of heritable pulmonary arterial hypertension
Abstract Bone morphogenetic protein receptor 2 (BMPR2) mutation is the most common gene mutation implicated in the pathogenesis of pulmonary arterial hypertension (PAH). We describe, for the first time, an excellent clinical response to tyrosine kinase inhibitor imatinib in a patient with heritable...
Main Authors: | Shine Kumar, Lalitha Biswas, Anju Choorakottayil Pushkaran, Raman Krishna Kumar |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2024-01-01
|
Series: | Pulmonary Circulation |
Subjects: | |
Online Access: | https://doi.org/10.1002/pul2.12335 |
Similar Items
-
A second hit? Pulmonary arterial hypertension, BMPR2 mutation, and exposure to prescription amphetamines
by: Huzaifa A. Jaliawala, et al.
Published: (2022-01-01) -
Compound BMPR2 gene mutations in a malignant variant of idiopathic pulmonary arterial hypertension
by: Walter Serra, et al.
Published: (2014-12-01) -
BMPR2 mutations and response to inhaled or parenteral prostanoids: a case series
by: Laura Scelsi, et al.
Published: (2021-10-01) -
Bmpr2 mutant mice are an inadequate model for studying iron deficiency in pulmonary hypertension
by: Vida Zhang, et al.
Published: (2022-10-01) -
BMPR1B gene in brachydactyly type 2–A family with de novo R486W mutation and a disease phenotype
by: Marcin Bednarek, et al.
Published: (2021-03-01)