Macroscopic Effect of Blue Light Cure on Wound Healing Process
Background: Wound healing is a complex process and a worldwide challenge. Some studies have suggested light cure as a modality to accelerate wound repair. It could induce fibroblast proliferation, increase collagen synthesis and activate cellular processes involved in expression of procollagen type...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2011-10-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/438 |
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| author | Mohammad Ali Nilforoushzadeh Vahid Changizi Homeira Mardani Parisa Kakanezhadian Faezeh Moshref Javadi Fariba Jaffary Elaheh Haftbaradaran |
| author_facet | Mohammad Ali Nilforoushzadeh Vahid Changizi Homeira Mardani Parisa Kakanezhadian Faezeh Moshref Javadi Fariba Jaffary Elaheh Haftbaradaran |
| author_sort | Mohammad Ali Nilforoushzadeh |
| collection | DOAJ |
| description | Background: Wound healing is a complex process and a worldwide challenge. Some studies have suggested light cure as a modality to accelerate wound repair. It could induce fibroblast proliferation, increase collagen synthesis and activate cellular processes involved in expression of procollagen type I and III mRNA. This study was designed to assess macroscopic effect of halogen dental curing blue light on a full thickness open wound healing in NMRI mices.
Methods: 40 male NMRI rats were divided into the control and treatment groups. Full thickness wound with 6 mm diameter was induced on the lower back of all mice under general anesthesia and sterile conditions. All mice of the treatment group were exposed daily to a halogen dental curing blue light with a wavelength of 420-500 nm, for 7 days. The diameter of the wound was measured in both treatment and control groups every 2 days up to day 14.
Findings: There was a significant difference in wound diameter between control and treatment group at all measurements after day 3 (P ≤ 0.05).
Conclusion: Previous studies have shown the efficacy of low level laser in wound healing, pain relief, increasing local blood supply, decreasing inflammation and bactericidal effect. The results of this study suggest improvement of full thickness wound healing by daily irradiation of halogen dental curing blue light with a wavelength 420-500 nm for 7 days. |
| first_indexed | 2024-03-12T10:29:26Z |
| format | Article |
| id | doaj.art-1b3e12f0b8e64120b67f258396316e2f |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T10:29:26Z |
| publishDate | 2011-10-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-1b3e12f0b8e64120b67f258396316e2f2023-09-02T09:20:56ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-10-012914910071013728Macroscopic Effect of Blue Light Cure on Wound Healing ProcessMohammad Ali Nilforoushzadeh0Vahid Changizi1Homeira Mardani2Parisa Kakanezhadian3Faezeh Moshref Javadi4Fariba Jaffary5Elaheh Haftbaradaran6Associate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran and Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, IranAssistant Professor, Department of Radiology and Medical Physics, School of Medicine, Tehran University of Medical Sciences, Tehran, IranAsistant Professor, Department of Dental Pathology, Khorasgan Branch, Islamic Azad University, Isfahan, IranDepartment of Biophysics, Science and Research Branch, Islamic Azad University of Tehran, Tehran, IranDepartment of Physiology , Science and Research Branch, Islamic Azad University of Tehran, Tehran, IranAssociate Professor, Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan and Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranResearcher, Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, IranBackground: Wound healing is a complex process and a worldwide challenge. Some studies have suggested light cure as a modality to accelerate wound repair. It could induce fibroblast proliferation, increase collagen synthesis and activate cellular processes involved in expression of procollagen type I and III mRNA. This study was designed to assess macroscopic effect of halogen dental curing blue light on a full thickness open wound healing in NMRI mices. Methods: 40 male NMRI rats were divided into the control and treatment groups. Full thickness wound with 6 mm diameter was induced on the lower back of all mice under general anesthesia and sterile conditions. All mice of the treatment group were exposed daily to a halogen dental curing blue light with a wavelength of 420-500 nm, for 7 days. The diameter of the wound was measured in both treatment and control groups every 2 days up to day 14. Findings: There was a significant difference in wound diameter between control and treatment group at all measurements after day 3 (P ≤ 0.05). Conclusion: Previous studies have shown the efficacy of low level laser in wound healing, pain relief, increasing local blood supply, decreasing inflammation and bactericidal effect. The results of this study suggest improvement of full thickness wound healing by daily irradiation of halogen dental curing blue light with a wavelength 420-500 nm for 7 days.http://jims.mui.ac.ir/index.php/jims/article/view/438Light cureWound healingNMRI mice |
| spellingShingle | Mohammad Ali Nilforoushzadeh Vahid Changizi Homeira Mardani Parisa Kakanezhadian Faezeh Moshref Javadi Fariba Jaffary Elaheh Haftbaradaran Macroscopic Effect of Blue Light Cure on Wound Healing Process مجله دانشکده پزشکی اصفهان Light cure Wound healing NMRI mice |
| title | Macroscopic Effect of Blue Light Cure on Wound Healing Process |
| title_full | Macroscopic Effect of Blue Light Cure on Wound Healing Process |
| title_fullStr | Macroscopic Effect of Blue Light Cure on Wound Healing Process |
| title_full_unstemmed | Macroscopic Effect of Blue Light Cure on Wound Healing Process |
| title_short | Macroscopic Effect of Blue Light Cure on Wound Healing Process |
| title_sort | macroscopic effect of blue light cure on wound healing process |
| topic | Light cure Wound healing NMRI mice |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/438 |
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