Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s disease
The incidence of inflammatory bowel disease (IBD) is rapidly increasing worldwide. Indigo naturalis is known to have an antiinflammatory effect. Indigo naturalis has been traditionally used in the treatment of IBD in China and Japan. Currently, it is used as a primary or adjunctive drug in patients...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Association for the Study of Intestinal Diseases
2019-01-01
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| Series: | Intestinal Research |
| Subjects: | |
| Online Access: | http://www.irjournal.org/upload/pdf/ir-2018-00104.pdf |
| _version_ | 1828453446631555072 |
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| author | Hyeon-A Kim Hyo-rim Suh Ben Kang Byung-Ho Choe |
| author_facet | Hyeon-A Kim Hyo-rim Suh Ben Kang Byung-Ho Choe |
| author_sort | Hyeon-A Kim |
| collection | DOAJ |
| description | The incidence of inflammatory bowel disease (IBD) is rapidly increasing worldwide. Indigo naturalis is known to have an antiinflammatory effect. Indigo naturalis has been traditionally used in the treatment of IBD in China and Japan. Currently, it is used as a primary or adjunctive drug in patients with ulcerative colitis. There are some reports of the effects of indigo naturalis when used in patients with ulcerative colitis. However, its usage has been associated with adverse events, including liver dysfunction, headache, gastrointestinal disturbance, and pulmonary hypertension. Pancreatitis as an adverse event during treatment using indigo naturalis has not yet been reported. We report a case of recurrent events of pancreatitis that occurred briefly after starting medication with indigo naturalis in a child with severe Crohn’s disease. The pancreatitis improved after indigo naturalis was discontinued in 2 events. This is the first case to report the association between pancreatitis and indigo naturalis in the English literature. |
| first_indexed | 2024-12-11T00:06:44Z |
| format | Article |
| id | doaj.art-1b44004f05bb4f23a44d46c283a46585 |
| institution | Directory Open Access Journal |
| issn | 1598-9100 2288-1956 |
| language | English |
| last_indexed | 2024-12-11T00:06:44Z |
| publishDate | 2019-01-01 |
| publisher | Korean Association for the Study of Intestinal Diseases |
| record_format | Article |
| series | Intestinal Research |
| spelling | doaj.art-1b44004f05bb4f23a44d46c283a465852022-12-22T01:28:17ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562019-01-0117114414810.5217/ir.2018.00104716Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s diseaseHyeon-A Kim0Hyo-rim Suh1Ben Kang2Byung-Ho Choe Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, KoreaThe incidence of inflammatory bowel disease (IBD) is rapidly increasing worldwide. Indigo naturalis is known to have an antiinflammatory effect. Indigo naturalis has been traditionally used in the treatment of IBD in China and Japan. Currently, it is used as a primary or adjunctive drug in patients with ulcerative colitis. There are some reports of the effects of indigo naturalis when used in patients with ulcerative colitis. However, its usage has been associated with adverse events, including liver dysfunction, headache, gastrointestinal disturbance, and pulmonary hypertension. Pancreatitis as an adverse event during treatment using indigo naturalis has not yet been reported. We report a case of recurrent events of pancreatitis that occurred briefly after starting medication with indigo naturalis in a child with severe Crohn’s disease. The pancreatitis improved after indigo naturalis was discontinued in 2 events. This is the first case to report the association between pancreatitis and indigo naturalis in the English literature.http://www.irjournal.org/upload/pdf/ir-2018-00104.pdfCrohn diseaseInflammatory bowel diseasePancreatitisChildKampo |
| spellingShingle | Hyeon-A Kim Hyo-rim Suh Ben Kang Byung-Ho Choe Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s disease Intestinal Research Crohn disease Inflammatory bowel disease Pancreatitis Child Kampo |
| title | Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s disease |
| title_full | Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s disease |
| title_fullStr | Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s disease |
| title_full_unstemmed | Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s disease |
| title_short | Acute pancreatitis associated with indigo naturalis in pediatric severe Crohn’s disease |
| title_sort | acute pancreatitis associated with indigo naturalis in pediatric severe crohn s disease |
| topic | Crohn disease Inflammatory bowel disease Pancreatitis Child Kampo |
| url | http://www.irjournal.org/upload/pdf/ir-2018-00104.pdf |
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