An empirical evaluation of the impact scenario of pooling bodies of evidence from randomized controlled trials and cohort studies in medical research

An empirical evaluation of the impact scenario of pooling bodies of evidence from randomized controlled trials and cohort studies in medical research

Abstract Background Randomized controlled trials (RCTs) and cohort studies are the most common study design types used to assess treatment effects of medical interventions. We aimed to hypothetically pool bodies of evidence (BoE) from RCTs with matched BoE from cohort studies included in the same sy...

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Bibliographic Details
Main Authors: Nils Bröckelmann, Julia Stadelmaier, Louisa Harms, Charlotte Kubiak, Jessica Beyerbach, Martin Wolkewitz, Jörg J. Meerpohl, Lukas Schwingshackl
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Medicine
Subjects:
General medicine
Pooling
Meta-analysis
Cohort studies
Randomized controlled trials
Online Access:https://doi.org/10.1186/s12916-022-02559-y

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