Antisense oligonucleotides: a novel Frontier in pharmacological strategy

Antisense oligonucleotides: a novel Frontier in pharmacological strategy

Antisense oligonucleotides (ASOs) are short single stranded synthetic RNA or DNA molecules, whereas double-stranded RNA nucleotide sequences are called small interfering RNA (siRNA). ASOs bind to complementary nucleic acid sequences impacting the associated functions of the targeted nucleic acids. T...

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Bibliographic Details
Main Authors: D. Collotta, I. Bertocchi, E. Chiapello, M. Collino
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
antisense oligonucleotide
siRNA
genetic disorder
gene silencing
pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1304342/full

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