The synergistic antibacterial activity and mechanism of colistin-oxethazaine combination against gram-negative pathogens

The synergistic antibacterial activity and mechanism of colistin-oxethazaine combination against gram-negative pathogens

Background:The rapid spread of bacteria with plasmid-mediated resistance to antibiotics poses a serious threat to public health. The search for potential compounds that can increase the antibacterial activity of existing antibiotics is a promising strategy for addressing this issue.Methods:Synergist...

Full description

Bibliographic Details
Main Authors:	Jie Li, Ning Han, Yangyang Li, Feifei Zhao, Wenguang Xiong, Zhenling Zeng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Pharmacology
Subjects:	antibiotic resistance drug combination colistin oxethazine gram-negative bacteria
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1363441/full

Similar Items

Mechanism of Action of Isopropoxy Benzene Guanidine against Multidrug-Resistant Pathogens
by: Jie Li, et al.
Published: (2023-02-01)

Synergistic antibacterial effects of closantel and its enantiomers in combination with colistin against multidrug resistant gram-negative bacteria
by: Tongyan Ding, et al.
Published: (2024-05-01)

The Antibacterial Activity of Kaempferol Combined with Colistin against Colistin-Resistant Gram-Negative Bacteria
by: Huijing Zhou, et al.
Published: (2022-12-01)

Exploring Structure–Activity Relationships of Niclosamide-Based Colistin Potentiators in Colistin-Resistant Gram-Negative Bacteria
by: Liam Berry, et al.
Published: (2024-01-01)

Naringenin restores colistin activation against colistin-resistant gram-negative bacteria in vitro and in vivo
by: Mengxin Xu, et al.
Published: (2022-08-01)

Intravenous Colistin Use for Multidrug-Resistant Gram-Negative Infections in Pediatric Patients
by: Ayşe Karaaslan, et al.
Published: (2016-12-01)

Colistin Loading Dose in Septic Patients with Gram Negative Infections
by: Alshaya AI, et al.
Published: (2022-04-01)

Assessment of colistin resistance among nosocomial multidrug-resistant Gram-negative bacilli isolated from different clinical samples
by: Hanaa Abdel-Aty, et al.
Published: (2024-11-01)

Clinical outcomes and safety of colistin in treatment of gram negative infections: A prospective observational study
by: Kinnari Desai, et al.
Published: (2016-08-01)

Optimising the dosing of antibiotics: Colistin and vancomycin updates
by: Reklia Solomon, et al.
Published: (2015-01-01)

Cost-effectiveness analysis of polymyxin B versus colistin for treating patients with carbapenem-resistant gram-negative bacterial infections
by: Ye Wang, et al.
Published: (2024-10-01)

Resistance mechanisms for Gram-negative bacteria-specific lipopeptides, turnercyclamycins, differ from that of colistin
by: Albebson L. Lim, et al.
Published: (2023-12-01)

Equisetin Restores Colistin Sensitivity against Multi-Drug Resistant Gram-Negative Bacteria
by: Qi Zhang, et al.
Published: (2021-10-01)

Inhaled colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria: A real-life experience in tertiary care hospitals in Saudi Arabia
by: Thamer A. Almangour, et al.
Published: (2020-08-01)

Re-emerging of colistin for treatment of nosocomial pneumonia due to gram negative multi-drug resistant pathogens in critically ill patients
by: Mohamed Amin, et al.
Published: (2013-07-01)

Dose Optimization of Colistin: A Systematic Review
by: Abdul Haseeb, et al.
Published: (2021-11-01)

Comprehensive insights into colistin and colistin resistance: updated regulations and policies on colistin usage and alternative strategies for mitigation and prevention of colistin resistance
by: Zine El abidine Bzazou El Ouazzani, et al.
Published: (2024-10-01)

Co-Existence of Oxazolidinone Resistance Genes <i>cfr</i>(D) and <i>optrA</i> on Two <i>Streptococcus parasuis</i> Isolates from Swine
by: Ning Han, et al.
Published: (2023-04-01)

In vitro and in vivo assessment of the antibacterial activity of colistin alone and in combination with other antibiotics against Acinetobacter baumannii and Escherichia coli
by: Yale Wang, et al.
Published: (2020-03-01)

Virulence Determinants and Plasmid-Mediated Colistin Resistance mcr Genes in Gram-Negative Bacteria Isolated From Bovine Milk
by: Yasmine H. Tartor, et al.
Published: (2021-11-01)

Blood Stream Infections caused by Non-Fermenting Gram Negative Bacilli, Clinical Correlation, MIC for Colistin, Gene Detection
by: Angel Varghese, et al.
Published: (2020-09-01)

Synergistic Activity of Colistin Combined With Auranofin Against Colistin-Resistant Gram-Negative Bacteria
by: Xiaoxuan Feng, et al.
Published: (2021-06-01)

Pharmacokinetics of colistin in patients with multi-drug resistant Gram-negative bacterial infections
by: Harivenkatesh Natarajan, et al.
Published: (2024-12-01)

Vegetables and Fruit as a Reservoir of β-Lactam and Colistin-Resistant Gram-Negative Bacteria: A Review
by: Widad Chelaghma, et al.
Published: (2021-12-01)

Combining Colistin with Furanone C-30 Rescues Colistin Resistance of Gram-Negative Bacteria in Vitro and in Vivo
by: Ying Zhang, et al.
Published: (2021-12-01)

Prevalence of Colistin-resistant Gram-negative Isolates Carrying the mcr-1 Gene among Patients Visiting a Tertiary Care Center
by: Ashmita Paudel, et al.
Published: (2020-12-01)

Ceftazidime/avibactam combined with colistin: a novel attempt to treat carbapenem-resistant Gram-negative bacilli infection
by: Zihao Zheng, et al.
Published: (2023-10-01)

Evaluation of the Efficacy of Colistin Therapy with or without Loading Dose in the Treatment of Multi Drug Resistant Gram-negative Bacterial Infections
by: Emine Kübra Dindar Demiray, et al.
Published: (2022-03-01)

Combination Regimens with Colistin Sulfate versus Colistin Sulfate Monotherapy in the Treatment of Infections Caused by Carbapenem-Resistant Gram-Negative Bacilli
by: Min Hao, et al.
Published: (2022-10-01)

Synergistic activity between colistin and the ionic liquids 1-methyl-3-dodecylimidazolium bromide, 1-dodecyl-1-methylpyrrolidinium bromide, or 1-dodecyl-1-methylpiperidinium bromide against Gram-negative bacteria
by: Walter Florio, et al.
Published: (2020-06-01)

In Vitro Activities of Colistin and Sitafloxacin Combinations against Multidrug-, Carbapenem-, and Colistin-Resistant <i>Acinetobacter baumannii</i> Using the Broth Microdilution Checkerboard and Time-Kill Methods
by: Vipavee Rodjun, et al.
Published: (2020-08-01)

Synergistic Activity of Colistin in Combination With Resveratrol Against Colistin-Resistant Gram-Negative Pathogens
by: Antonio Cannatelli, et al.
Published: (2018-08-01)

Evaluation of Co-production of Colistin Resistance and ESBL Genes among Gram-negative Clinical Isolates from Usmanu Danfodiyo University Teaching Hospital Sokoto, Nigeria
by: Tanko Nuhu, et al.
Published: (2024-06-01)

Colistin Resistance Burden among Clinical Isolates of Gram-negative Rods: A Systematic Review and Meta-analysis
by: Razieh Amirfakhrian, et al.
Published: (2020-06-01)

Colistin Resistance Burden among Clinical Isolates of Gram-negative Rods: A Systematic Review and Meta-analysis
by: Razieh Amirfakhrian, et al.
Published: (2020-04-01)

Detection of PhoP-mediated colistin resistance in Gram-negative bacteria without mcr genes in human population in the Ho Municipality, Ghana
by: Emmanuel U. Osisiogu, et al.
Published: (2024-11-01)

The Antimicrobial Effects of Colistin Encapsulated in Chelating Complex Micelles for the Treatment of Multi-Drug-Resistant Gram-Negative Bacteria: A Pharmacokinetic Study
by: Wei-Chuan Liao, et al.
Published: (2023-04-01)

Lacticaseicin 30 and Colistin as a Promising Antibiotic Formulation against Gram-Negative β-Lactamase-Producing Strains and Colistin-Resistant Strains
by: Désiré Madi-Moussa, et al.
Published: (2021-12-01)

CXC Chemokines Exhibit Bactericidal Activity against Multidrug-Resistant Gram-Negative Pathogens
by: Matthew A. Crawford, et al.
Published: (2017-12-01)

Research Note: Synergistic effect of isopropoxy benzene guanidine and colistin against mcr-1-positive Escherichia coli in vitro and in duck intestine infection models
by: Yafei Li, et al.
Published: (2024-09-01)