Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic Dilemma

Sertoli Leydig Cell Tumours (SLCTs) are rare, unilateral, sex cord stromal tumours of ovary, which constitute less than 1% of all the ovarian neoplasms. These tumours can be functionally diverse and they may have heterologous elements. We aim to report a case of a 25-yearold woman who presented wit...

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Main Authors: Rohini Dhanya C.S., Somanath Padhi, Renu G’Boy Varghese
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2014-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/4099/42-%207000_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(PUH)_PFA2(AK)_PF2(PN).pdf
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author Rohini Dhanya C.S.
Somanath Padhi
Renu G’Boy Varghese
author_facet Rohini Dhanya C.S.
Somanath Padhi
Renu G’Boy Varghese
author_sort Rohini Dhanya C.S.
collection DOAJ
description Sertoli Leydig Cell Tumours (SLCTs) are rare, unilateral, sex cord stromal tumours of ovary, which constitute less than 1% of all the ovarian neoplasms. These tumours can be functionally diverse and they may have heterologous elements. We aim to report a case of a 25-yearold woman who presented with suprapubic pain of 5 days duration, a unilateral adnexal mass, hypertestosteronism without virilization. Intraoperative frozen section of the unilateral salpingo-oophorectomy specimen was suggestive of granulosa cell tumour. Histopathological examination, supplemented with alpha-inhibin immunohistochemistry, was diagnostic of Meyer’s type II SLCT. Clinical presentation, pathology and the diagnostic pitfalls in the present case have been presented with a brief review of literature.
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spelling doaj.art-1b51fe99df4442e2bee18a07f6f2d2032022-12-22T01:48:53ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-03-018312712910.7860/JCDR/2014/7000.4099Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic DilemmaRohini Dhanya C.S.0Somanath Padhi1Renu G’Boy Varghese2Tutor, Department of Pathology, Dr. B.R. Ambedkar Medical College and Hospital, Bangalore, India, Ex-Senior Resident, Department of Pathology, Pondicherry Institute of Medical Sciences, Ganapathychettykulam, Kalapet, Puducherry, India.Assistant Professor, Department of Pathology, Pondicherry Institute of Medical Sciences, Ganapathychettykulam, Kalapet, Puducherry, India.Professor and HOD, Department of Pathology, Pondicherry Institute of Medical Sciences, Ganapathychettykulam, Kalapet, Puducherry, India. Sertoli Leydig Cell Tumours (SLCTs) are rare, unilateral, sex cord stromal tumours of ovary, which constitute less than 1% of all the ovarian neoplasms. These tumours can be functionally diverse and they may have heterologous elements. We aim to report a case of a 25-yearold woman who presented with suprapubic pain of 5 days duration, a unilateral adnexal mass, hypertestosteronism without virilization. Intraoperative frozen section of the unilateral salpingo-oophorectomy specimen was suggestive of granulosa cell tumour. Histopathological examination, supplemented with alpha-inhibin immunohistochemistry, was diagnostic of Meyer’s type II SLCT. Clinical presentation, pathology and the diagnostic pitfalls in the present case have been presented with a brief review of literature.https://jcdr.net/articles/PDF/4099/42-%207000_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(PUH)_PFA2(AK)_PF2(PN).pdfsertoli-leydig cell tumourovaryalfa-inhibinfrozen section
spellingShingle Rohini Dhanya C.S.
Somanath Padhi
Renu G’Boy Varghese
Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic Dilemma
Journal of Clinical and Diagnostic Research
sertoli-leydig cell tumour
ovary
alfa-inhibin
frozen section
title Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic Dilemma
title_full Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic Dilemma
title_fullStr Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic Dilemma
title_full_unstemmed Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic Dilemma
title_short Sertoli-Leydig Cell Tumor of Ovary-A Diagnostic Dilemma
title_sort sertoli leydig cell tumor of ovary a diagnostic dilemma
topic sertoli-leydig cell tumour
ovary
alfa-inhibin
frozen section
url https://jcdr.net/articles/PDF/4099/42-%207000_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(PUH)_PFA2(AK)_PF2(PN).pdf
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