Spatial modulation of visual responses arises in cortex with active navigation
During navigation, the visual responses of neurons in mouse primary visual cortex (V1) are modulated by the animal’s spatial position. Here we show that this spatial modulation is similarly present across multiple higher visual areas but negligible in the main thalamic pathway into V1. Similar to hi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2021-02-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/63705 |
| _version_ | 1818028496793894912 |
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| author | E Mika Diamanti Charu Bai Reddy Sylvia Schröder Tomaso Muzzu Kenneth D Harris Aman B Saleem Matteo Carandini |
| author_facet | E Mika Diamanti Charu Bai Reddy Sylvia Schröder Tomaso Muzzu Kenneth D Harris Aman B Saleem Matteo Carandini |
| author_sort | E Mika Diamanti |
| collection | DOAJ |
| description | During navigation, the visual responses of neurons in mouse primary visual cortex (V1) are modulated by the animal’s spatial position. Here we show that this spatial modulation is similarly present across multiple higher visual areas but negligible in the main thalamic pathway into V1. Similar to hippocampus, spatial modulation in visual cortex strengthens with experience and with active behavior. Active navigation in a familiar environment, therefore, enhances the spatial modulation of visual signals starting in the cortex. |
| first_indexed | 2024-12-10T05:04:43Z |
| format | Article |
| id | doaj.art-1b552bbab9574942b014e673ee73737c |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-12-10T05:04:43Z |
| publishDate | 2021-02-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-1b552bbab9574942b014e673ee73737c2022-12-22T02:01:16ZengeLife Sciences Publications LtdeLife2050-084X2021-02-011010.7554/eLife.63705Spatial modulation of visual responses arises in cortex with active navigationE Mika Diamanti0https://orcid.org/0000-0003-1199-3362Charu Bai Reddy1https://orcid.org/0000-0002-8195-3326Sylvia Schröder2https://orcid.org/0000-0002-9938-3931Tomaso Muzzu3https://orcid.org/0000-0002-0018-8416Kenneth D Harris4https://orcid.org/0000-0002-5930-6456Aman B Saleem5https://orcid.org/0000-0002-7100-1954Matteo Carandini6https://orcid.org/0000-0003-4880-7682UCL Institute of Ophthalmology, University College London, London, United Kingdom; CoMPLEX, Department of Computer Science, University College London, London, United KingdomUCL Institute of Ophthalmology, University College London, London, United KingdomUCL Institute of Ophthalmology, University College London, London, United KingdomUCL Institute of Behavioural Neuroscience, University College London, London, United KingdomUCL Queen Square Institute of Neurology, University College London, London, United KingdomUCL Institute of Behavioural Neuroscience, University College London, London, United KingdomUCL Institute of Ophthalmology, University College London, London, United KingdomDuring navigation, the visual responses of neurons in mouse primary visual cortex (V1) are modulated by the animal’s spatial position. Here we show that this spatial modulation is similarly present across multiple higher visual areas but negligible in the main thalamic pathway into V1. Similar to hippocampus, spatial modulation in visual cortex strengthens with experience and with active behavior. Active navigation in a familiar environment, therefore, enhances the spatial modulation of visual signals starting in the cortex.https://elifesciences.org/articles/63705LGNV1higher visual areasnavigationspatial modulationvisual processing |
| spellingShingle | E Mika Diamanti Charu Bai Reddy Sylvia Schröder Tomaso Muzzu Kenneth D Harris Aman B Saleem Matteo Carandini Spatial modulation of visual responses arises in cortex with active navigation eLife LGN V1 higher visual areas navigation spatial modulation visual processing |
| title | Spatial modulation of visual responses arises in cortex with active navigation |
| title_full | Spatial modulation of visual responses arises in cortex with active navigation |
| title_fullStr | Spatial modulation of visual responses arises in cortex with active navigation |
| title_full_unstemmed | Spatial modulation of visual responses arises in cortex with active navigation |
| title_short | Spatial modulation of visual responses arises in cortex with active navigation |
| title_sort | spatial modulation of visual responses arises in cortex with active navigation |
| topic | LGN V1 higher visual areas navigation spatial modulation visual processing |
| url | https://elifesciences.org/articles/63705 |
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