Ezrin Contributes to the Plasma Membrane Expression of PD–L1 in A2780 Cells

Ezrin Contributes to the Plasma Membrane Expression of PD–L1 in A2780 Cells

Programmed death ligand–1 (PD–L1) is one of the immune checkpoint molecule localized on the plasma membrane of numerous cancer cells that negatively regulates T-cell-mediated immunosurveillance. Despite the remarkable efficacy and safety profile of immune checkpoint inhibitors (ICIs), such as anti-P...

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Bibliographic Details
Main Authors: Mayuka Tameishi, Honami Ishikawa, Chihiro Tanaka, Takuro Kobori, Yoko Urashima, Takuya Ito, Tokio Obata
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Journal of Clinical Medicine
Subjects:
programmed death ligand–1
immune checkpoint molecules
ezrin
radixin
moesin
ovarian cancer
Online Access:https://www.mdpi.com/2077-0383/11/9/2457

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