Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing

Antibacterial wound healing approaches often target bacteria but overlook the inflammation response caused by products release by dead bacteria. Here, the authors report on the development of Boride nanoparticles to treat infection and prevent excessive inflammation by trapping lipopolysaccharides/p...

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Main Authors: Yun Meng, Lijie Chen, Yang Chen, Jieyun Shi, Zheng Zhang, Yiwen Wang, Fan Wu, Xingwu Jiang, Wei Yang, Li Zhang, Chaochao Wang, Xianfu Meng, Yelin Wu, Wenbo Bu
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35050-6
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author Yun Meng
Lijie Chen
Yang Chen
Jieyun Shi
Zheng Zhang
Yiwen Wang
Fan Wu
Xingwu Jiang
Wei Yang
Li Zhang
Chaochao Wang
Xianfu Meng
Yelin Wu
Wenbo Bu
author_facet Yun Meng
Lijie Chen
Yang Chen
Jieyun Shi
Zheng Zhang
Yiwen Wang
Fan Wu
Xingwu Jiang
Wei Yang
Li Zhang
Chaochao Wang
Xianfu Meng
Yelin Wu
Wenbo Bu
author_sort Yun Meng
collection DOAJ
description Antibacterial wound healing approaches often target bacteria but overlook the inflammation response caused by products release by dead bacteria. Here, the authors report on the development of Boride nanoparticles to treat infection and prevent excessive inflammation by trapping lipopolysaccharides/peptidoglycans.
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spelling doaj.art-1b57d62faf874a459a545bcd0becf5af2022-12-22T04:17:31ZengNature PortfolioNature Communications2041-17232022-11-0113111610.1038/s41467-022-35050-6Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healingYun Meng0Lijie Chen1Yang Chen2Jieyun Shi3Zheng Zhang4Yiwen Wang5Fan Wu6Xingwu Jiang7Wei Yang8Li Zhang9Chaochao Wang10Xianfu Meng11Yelin Wu12Wenbo Bu13Tongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Fudan UniversityTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineSchool of Life Science, East China Normal UniversitySchool of Life Science, East China Normal UniversityDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Fudan UniversityDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Fudan UniversityTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineTongji University Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of MedicineAntibacterial wound healing approaches often target bacteria but overlook the inflammation response caused by products release by dead bacteria. Here, the authors report on the development of Boride nanoparticles to treat infection and prevent excessive inflammation by trapping lipopolysaccharides/peptidoglycans.https://doi.org/10.1038/s41467-022-35050-6
spellingShingle Yun Meng
Lijie Chen
Yang Chen
Jieyun Shi
Zheng Zhang
Yiwen Wang
Fan Wu
Xingwu Jiang
Wei Yang
Li Zhang
Chaochao Wang
Xianfu Meng
Yelin Wu
Wenbo Bu
Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing
Nature Communications
title Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing
title_full Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing
title_fullStr Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing
title_full_unstemmed Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing
title_short Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing
title_sort reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria infected wound healing
url https://doi.org/10.1038/s41467-022-35050-6
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