Blast-Induced Tinnitus and Elevated Central Auditory and Limbic Activity in Rats: A Manganese-Enhanced MRI and Behavioral Study
Abstract Blast-induced tinitus is the number one service-connected disability that currently affects military personnel and veterans. To elucidate its underlying mechanisms, we subjected 13 Sprague Dawley adult rats to unilateral 14 psi blast exposure to induce tinnitus and measured auditory and lim...
Main Authors: | Jessica Ouyang, Edward Pace, Laura Lepczyk, Michael Kaufman, Jessica Zhang, Shane A. Perrine, Jinsheng Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-07-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-04941-w |
Similar Items
-
Tinnitus and hyperacusis involve hyperactivity and enhanced connectivity in auditory-limbic-arousal-cerebellar network
by: Yu-Chen Chen, et al.
Published: (2015-05-01) -
Cortico-limbic morphology separates tinnitus from tinnitus distress
by: Amber M Leaver, et al.
Published: (2012-04-01) -
Time course of blast-induced injury in the rat auditory cortex.
by: Srinivasu Kallakuri, et al.
Published: (2018-01-01) -
Targeting the Limbic System: Insights into Its Involvement in Tinnitus
by: Anurag Singh, et al.
Published: (2023-06-01) -
Noise-induced tinnitus using individualized gap detection analysis and its relationship with hyperacusis, anxiety, and spatial cognition.
by: Edward Pace, et al.
Published: (2013-01-01)