Protocol optimization of a targeted sequencing panel for genomic profiling of bronchoalveolar lavage fluid in lung cancer

Protocol optimization of a targeted sequencing panel for genomic profiling of bronchoalveolar lavage fluid in lung cancer

Abstract Introduction We investigated a commercially available sequencing panel to study the effect of sequencing depth, variant calling strategy, and targeted sequencing region on identifying tumor‐derived variants in cell‐free bronchoalveolar lavage (cfBAL) DNA compared with plasma cfDNA. Methods...

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Bibliographic Details
Main Authors: Cassandra L. Sather, Pamela Yang, Chaomei Zhang, Matthew P. Fitzgibbon, Michelle Fournier, Eric Toloza, Amit Tandon, Matthew Schabath, Sean Yoder, Viswam S. Nair
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Cancer Medicine
Subjects:
AVENIO®
BAL
CAPP‐Seq
genomics
lung cancer
Online Access:https://doi.org/10.1002/cam4.6380

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