Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty

Various failure mechanisms have been identified in total knee arthroplasty (TKA). We hereby present one case of failure, which stands out because of its rapid and destructive progression. We report the case of a 72-year-old Caucasian female patient who developed a large bone osteolytic lesion of the...

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Main Authors: Afonso Cardoso, MD, Pedro Amaro, MD, Patrícia Gamelas, MD, Rita Carvalho e Silva, MD, Maria Helena Oliveira, MD, Marcos Correia de Jesus, MD
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Arthroplasty Today
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235234412030100X
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author Afonso Cardoso, MD
Pedro Amaro, MD
Patrícia Gamelas, MD
Rita Carvalho e Silva, MD
Maria Helena Oliveira, MD
Marcos Correia de Jesus, MD
author_facet Afonso Cardoso, MD
Pedro Amaro, MD
Patrícia Gamelas, MD
Rita Carvalho e Silva, MD
Maria Helena Oliveira, MD
Marcos Correia de Jesus, MD
author_sort Afonso Cardoso, MD
collection DOAJ
description Various failure mechanisms have been identified in total knee arthroplasty (TKA). We hereby present one case of failure, which stands out because of its rapid and destructive progression. We report the case of a 72-year-old Caucasian female patient who developed a large bone osteolytic lesion of the femur after TKA. The patient presented to our hospital 7 years after the initial surgery, complaining of persistent knee pain. The lesion affected the distal half of the femur and, after a diagnostic workup, required a resection of 20 cm and reconstruction with a tumor prosthesis. Subsequent pathological analysis revealed a reaction to cement and prosthesis components. Periprosthetic osteolysis continues to be a major problem, and a reaction to cement and prosthesis components can be an elusive cause of TKA failure.
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spelling doaj.art-1b6105cd716045039ae96ebf1f67fe7f2022-12-21T23:33:59ZengElsevierArthroplasty Today2352-34412020-09-0163463469Massive Osteolytic Lesion of the Femur after Total Knee ArthroplastyAfonso Cardoso, MD0Pedro Amaro, MD1Patrícia Gamelas, MD2Rita Carvalho e Silva, MD3Maria Helena Oliveira, MD4Marcos Correia de Jesus, MD5Orthopaedics Department, Hospital Beatriz Ângelo, Loures, Portugal; Corresponding author. Av. Carlos Teixeira 514, 2674 Loures, Portugal. Tel.: +351 219847209.Orthopaedics Department, Hospital Beatriz Ângelo, Loures, PortugalOrthopaedics Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, PortugalOrthopaedics Department, Hospital Beatriz Ângelo, Loures, PortugalDepartment of Pathological Anatomy, Hospital Beatriz Ângelo, Loures, PortugalOrthopaedics Department, Hospital Beatriz Ângelo, Loures, PortugalVarious failure mechanisms have been identified in total knee arthroplasty (TKA). We hereby present one case of failure, which stands out because of its rapid and destructive progression. We report the case of a 72-year-old Caucasian female patient who developed a large bone osteolytic lesion of the femur after TKA. The patient presented to our hospital 7 years after the initial surgery, complaining of persistent knee pain. The lesion affected the distal half of the femur and, after a diagnostic workup, required a resection of 20 cm and reconstruction with a tumor prosthesis. Subsequent pathological analysis revealed a reaction to cement and prosthesis components. Periprosthetic osteolysis continues to be a major problem, and a reaction to cement and prosthesis components can be an elusive cause of TKA failure.http://www.sciencedirect.com/science/article/pii/S235234412030100XTotal knee arthroplastyOsteolytic femoral lesionLimb preservation prosthesis
spellingShingle Afonso Cardoso, MD
Pedro Amaro, MD
Patrícia Gamelas, MD
Rita Carvalho e Silva, MD
Maria Helena Oliveira, MD
Marcos Correia de Jesus, MD
Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty
Arthroplasty Today
Total knee arthroplasty
Osteolytic femoral lesion
Limb preservation prosthesis
title Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty
title_full Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty
title_fullStr Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty
title_full_unstemmed Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty
title_short Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty
title_sort massive osteolytic lesion of the femur after total knee arthroplasty
topic Total knee arthroplasty
Osteolytic femoral lesion
Limb preservation prosthesis
url http://www.sciencedirect.com/science/article/pii/S235234412030100X
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