Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lamb
Selenium play a crucial role in the formation of selenoprotein, hormones and intrinsic factors. The stearoyl-CoA desaturase enzyme (SCD) is present in many tissues of the body and its activity leads to the formation of a single-stranded fatty acid from saturated fatty acids. Present study was carrie...
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| Format: | Article |
| Language: | fas |
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Islamic Azad University, Tabriz Branch
2020-04-01
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| Series: | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
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| Online Access: | http://jvcp.iaut.ac.ir/article_674451_13e575afca042eba171b467cfa31e30f.pdf |
| _version_ | 1818241435461222400 |
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| author | Hamid Esmaeeli Najafabadi Gholamali Kojouri Ali mohammad Ahadi |
| author_facet | Hamid Esmaeeli Najafabadi Gholamali Kojouri Ali mohammad Ahadi |
| author_sort | Hamid Esmaeeli Najafabadi |
| collection | DOAJ |
| description | Selenium play a crucial role in the formation of selenoprotein, hormones and intrinsic factors. The stearoyl-CoA desaturase enzyme (SCD) is present in many tissues of the body and its activity leads to the formation of a single-stranded fatty acid from saturated fatty acids. Present study was carried out on fat tail weaning male lambs to evaluate the effect of oral selenium nanoparticles administration on transcription rate of stearoyl-CoA desaturase enzyme. For this purpose, 14 male lambs were selected at weaning time and divided into three groups: treatment 1 (5 heads), treatment 2 (5 heads) and control (4 heads). Selenium nanoparticles were administered for 20 consecutive days at a dose of 0.05 and 0.1 mg/kg B.W. to treatment groups 1 and 2, respectively and distilled water to the control ones. Tail fat tissue samples were collected at days 0, 20 and 30 via core biopsy needle gauge 14. Transcription rate of stearoyl-CoA desaturase (SCD) enzyme gene was performed by RT-PCR method and data were analyzed statistically using ANOVA test at the level of p |
| first_indexed | 2024-12-12T13:29:18Z |
| format | Article |
| id | doaj.art-1b62e26fa4ca457989e269a96c4a1bfa |
| institution | Directory Open Access Journal |
| issn | 2322-4746 2476-6984 |
| language | fas |
| last_indexed | 2024-12-12T13:29:18Z |
| publishDate | 2020-04-01 |
| publisher | Islamic Azad University, Tabriz Branch |
| record_format | Article |
| series | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
| spelling | doaj.art-1b62e26fa4ca457989e269a96c4a1bfa2022-12-22T00:23:06ZfasIslamic Azad University, Tabriz BranchĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī2322-47462476-69842020-04-01141 (53) بهار738310.30495/jvcp.2020.1865659.1228674451Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lambHamid Esmaeeli Najafabadi0Gholamali Kojouri1Ali mohammad Ahadi2PhD Student, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.Professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.Associate Professor, Department of Genetics, Faculty of Basic Sciences, Shahrekord University, Shahrekord, Iran.Selenium play a crucial role in the formation of selenoprotein, hormones and intrinsic factors. The stearoyl-CoA desaturase enzyme (SCD) is present in many tissues of the body and its activity leads to the formation of a single-stranded fatty acid from saturated fatty acids. Present study was carried out on fat tail weaning male lambs to evaluate the effect of oral selenium nanoparticles administration on transcription rate of stearoyl-CoA desaturase enzyme. For this purpose, 14 male lambs were selected at weaning time and divided into three groups: treatment 1 (5 heads), treatment 2 (5 heads) and control (4 heads). Selenium nanoparticles were administered for 20 consecutive days at a dose of 0.05 and 0.1 mg/kg B.W. to treatment groups 1 and 2, respectively and distilled water to the control ones. Tail fat tissue samples were collected at days 0, 20 and 30 via core biopsy needle gauge 14. Transcription rate of stearoyl-CoA desaturase (SCD) enzyme gene was performed by RT-PCR method and data were analyzed statistically using ANOVA test at the level of phttp://jvcp.iaut.ac.ir/article_674451_13e575afca042eba171b467cfa31e30f.pdfselenium nanoparticlesstearoyl coa enzymetail fat tissuelamb |
| spellingShingle | Hamid Esmaeeli Najafabadi Gholamali Kojouri Ali mohammad Ahadi Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lamb Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī selenium nanoparticles stearoyl coa enzyme tail fat tissue lamb |
| title | Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lamb |
| title_full | Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lamb |
| title_fullStr | Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lamb |
| title_full_unstemmed | Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lamb |
| title_short | Selenium nanoparticles effects on stearoyl-CoA desaturase gene transcription rate in male lamb |
| title_sort | selenium nanoparticles effects on stearoyl coa desaturase gene transcription rate in male lamb |
| topic | selenium nanoparticles stearoyl coa enzyme tail fat tissue lamb |
| url | http://jvcp.iaut.ac.ir/article_674451_13e575afca042eba171b467cfa31e30f.pdf |
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