Total immunoglobulin E as marker of allergy at Northeast of Mexico
Background: Relationship of total serum IgE and allergy has been studied to determine if it could be a useful complement allergy diagnosis. Objective: To determine whether serum total IgE is a useful tool in diagnosis of allergy in pediatric population attending outpatient pediatric allergy Regiona...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2016-03-01
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| Series: | Revista Alergia México |
| Subjects: | |
| Online Access: | http://revistaalergia.mx/ojs/index.php/ram/article/view/135 |
| Summary: | Background: Relationship of total serum IgE and allergy has been studied to determine if it could be a useful complement allergy diagnosis.
Objective: To determine whether serum total IgE is a useful tool in diagnosis of allergy in pediatric population attending outpatient pediatric allergy Regional General Hospital No. 1, Ciudad Obregón, Sonora, Mexico.
Material and method: An epidemiological, observational, retrospective, transversal and analytical study of diagnostic test was done including files of children 3-15 years 11 months old, treated in pediatric allergy. For statistical analysis SPSS V-22 was used and through tetrachoric table, sensitivity, specificity of IgE for allergy diagnosis were determined, taking skin tests as a gold standard for diagnosing allergies; p value between the study variables was determined using Student t test.
Results: 248 records were studied; male gender was more frequent (59%). IgE sensitivity was 85% and specificity was 20%, cutoff point found was 148 IU/mL, elevated levels of IgE in skin tests to airborne allergens and presence of respiratory symptoms.
Conclusions: IgE determination is a useful initial screening test in patients with suspected allergy. |
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| ISSN: | 0002-5151 2448-9190 |