Immune microenvironment and immunotherapy of pituitary adenomas

Pituitary adenomas (PAs) are the second most common primary central nervous system tumors. Although most PAs can be cured by surgical operation, medicine treatment or radiotherapy, some PAs may recur, invade adjacent structures or even metastasize to other organs after traditional treatments, so dec...

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Main Author: GUO Xiao-peng, XING Bing, MA Wen-bin
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-01-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-173.pdf
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author GUO Xiao-peng, XING Bing, MA Wen-bin
author_facet GUO Xiao-peng, XING Bing, MA Wen-bin
author_sort GUO Xiao-peng, XING Bing, MA Wen-bin
collection DOAJ
description Pituitary adenomas (PAs) are the second most common primary central nervous system tumors. Although most PAs can be cured by surgical operation, medicine treatment or radiotherapy, some PAs may recur, invade adjacent structures or even metastasize to other organs after traditional treatments, so decreaseing patient overall survival and deteriorate their life quality. In recent years, studies on the immune microenvironment of brain tumors emerged, especially in the field of glioma, providing potential effective treatment targets for immunotherapy and setting the foundation for improving patient survival. However, previous studies have only conducted preliminary analyses on immune cells, immune molecules, and cytokines in the microenvironment of PAs. The research on immunotherapy of PAs with animal model and humans is only at an early phase.
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spelling doaj.art-1b668254585144cfbe17e76108fc7d402024-01-05T02:33:55ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252022-01-0142117317810.16352/j.issn.1001-6325.2022.01.034Immune microenvironment and immunotherapy of pituitary adenomasGUO Xiao-peng, XING Bing, MA Wen-bin0Department of Neurosurgery, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730, ChinaPituitary adenomas (PAs) are the second most common primary central nervous system tumors. Although most PAs can be cured by surgical operation, medicine treatment or radiotherapy, some PAs may recur, invade adjacent structures or even metastasize to other organs after traditional treatments, so decreaseing patient overall survival and deteriorate their life quality. In recent years, studies on the immune microenvironment of brain tumors emerged, especially in the field of glioma, providing potential effective treatment targets for immunotherapy and setting the foundation for improving patient survival. However, previous studies have only conducted preliminary analyses on immune cells, immune molecules, and cytokines in the microenvironment of PAs. The research on immunotherapy of PAs with animal model and humans is only at an early phase.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-173.pdfpituitary adenoma|immune microenvironment|immunotherapy
spellingShingle GUO Xiao-peng, XING Bing, MA Wen-bin
Immune microenvironment and immunotherapy of pituitary adenomas
Jichu yixue yu linchuang
pituitary adenoma|immune microenvironment|immunotherapy
title Immune microenvironment and immunotherapy of pituitary adenomas
title_full Immune microenvironment and immunotherapy of pituitary adenomas
title_fullStr Immune microenvironment and immunotherapy of pituitary adenomas
title_full_unstemmed Immune microenvironment and immunotherapy of pituitary adenomas
title_short Immune microenvironment and immunotherapy of pituitary adenomas
title_sort immune microenvironment and immunotherapy of pituitary adenomas
topic pituitary adenoma|immune microenvironment|immunotherapy
url http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-173.pdf
work_keys_str_mv AT guoxiaopengxingbingmawenbin immunemicroenvironmentandimmunotherapyofpituitaryadenomas