Immune microenvironment and immunotherapy of pituitary adenomas
Pituitary adenomas (PAs) are the second most common primary central nervous system tumors. Although most PAs can be cured by surgical operation, medicine treatment or radiotherapy, some PAs may recur, invade adjacent structures or even metastasize to other organs after traditional treatments, so dec...
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Format: | Article |
Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2022-01-01
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Series: | Jichu yixue yu linchuang |
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Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-173.pdf |
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author | GUO Xiao-peng, XING Bing, MA Wen-bin |
author_facet | GUO Xiao-peng, XING Bing, MA Wen-bin |
author_sort | GUO Xiao-peng, XING Bing, MA Wen-bin |
collection | DOAJ |
description | Pituitary adenomas (PAs) are the second most common primary central nervous system tumors. Although most PAs can be cured by surgical operation, medicine treatment or radiotherapy, some PAs may recur, invade adjacent structures or even metastasize to other organs after traditional treatments, so decreaseing patient overall survival and deteriorate their life quality. In recent years, studies on the immune microenvironment of brain tumors emerged, especially in the field of glioma, providing potential effective treatment targets for immunotherapy and setting the foundation for improving patient survival. However, previous studies have only conducted preliminary analyses on immune cells, immune molecules, and cytokines in the microenvironment of PAs. The research on immunotherapy of PAs with animal model and humans is only at an early phase. |
first_indexed | 2024-03-08T16:55:34Z |
format | Article |
id | doaj.art-1b668254585144cfbe17e76108fc7d40 |
institution | Directory Open Access Journal |
issn | 1001-6325 |
language | zho |
last_indexed | 2024-03-08T16:55:34Z |
publishDate | 2022-01-01 |
publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
record_format | Article |
series | Jichu yixue yu linchuang |
spelling | doaj.art-1b668254585144cfbe17e76108fc7d402024-01-05T02:33:55ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252022-01-0142117317810.16352/j.issn.1001-6325.2022.01.034Immune microenvironment and immunotherapy of pituitary adenomasGUO Xiao-peng, XING Bing, MA Wen-bin0Department of Neurosurgery, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730, ChinaPituitary adenomas (PAs) are the second most common primary central nervous system tumors. Although most PAs can be cured by surgical operation, medicine treatment or radiotherapy, some PAs may recur, invade adjacent structures or even metastasize to other organs after traditional treatments, so decreaseing patient overall survival and deteriorate their life quality. In recent years, studies on the immune microenvironment of brain tumors emerged, especially in the field of glioma, providing potential effective treatment targets for immunotherapy and setting the foundation for improving patient survival. However, previous studies have only conducted preliminary analyses on immune cells, immune molecules, and cytokines in the microenvironment of PAs. The research on immunotherapy of PAs with animal model and humans is only at an early phase.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-173.pdfpituitary adenoma|immune microenvironment|immunotherapy |
spellingShingle | GUO Xiao-peng, XING Bing, MA Wen-bin Immune microenvironment and immunotherapy of pituitary adenomas Jichu yixue yu linchuang pituitary adenoma|immune microenvironment|immunotherapy |
title | Immune microenvironment and immunotherapy of pituitary adenomas |
title_full | Immune microenvironment and immunotherapy of pituitary adenomas |
title_fullStr | Immune microenvironment and immunotherapy of pituitary adenomas |
title_full_unstemmed | Immune microenvironment and immunotherapy of pituitary adenomas |
title_short | Immune microenvironment and immunotherapy of pituitary adenomas |
title_sort | immune microenvironment and immunotherapy of pituitary adenomas |
topic | pituitary adenoma|immune microenvironment|immunotherapy |
url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-173.pdf |
work_keys_str_mv | AT guoxiaopengxingbingmawenbin immunemicroenvironmentandimmunotherapyofpituitaryadenomas |