Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial

Introduction: The growing field of alternative medicine has shown that dentifrices based on plant extracts are available in the market but there is little or no research to prove or refute the efficacy of dentifrices containing combination of herbal components. Aim: The study was conducted to evalua...

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Main Authors: Puneet Gupta, Nupur Agarwal, N Anup, B C Manujunath, Anindya Bhalla
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=4;spage=282;epage=285;aulast=Gupta
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author Puneet Gupta
Nupur Agarwal
N Anup
B C Manujunath
Anindya Bhalla
author_facet Puneet Gupta
Nupur Agarwal
N Anup
B C Manujunath
Anindya Bhalla
author_sort Puneet Gupta
collection DOAJ
description Introduction: The growing field of alternative medicine has shown that dentifrices based on plant extracts are available in the market but there is little or no research to prove or refute the efficacy of dentifrices containing combination of herbal components. Aim: The study was conducted to evaluate the anti-plaque efficacy of a commercially available Meswak containing dentifrice compared to the conventional dentifrice using a randomized, triple blind, parallel design method. Materials and Methods: A total of 350 subjects were selected. All the subjects (aged 13-54 years) were given the test dentifrices, packed in plain white color-coded tubes. The subjects were instructed to brush their teeth twice daily for 2 min with the allocated dentifrice. The total study duration was 4 weeks. Plaque scores were recorded at the baseline, 2 weeks and 4 weeks respectively, using the Turesky modification of the Quigley Hein Plaque Index. Results: The results showed that there were significant differences in the reduction of plaque by the herbal dentifrice, Meswak (Salvadora persica) on intra-group and inter-group comparison. Conclusion: It was concluded that further research is required to know the dental benefits of herbal products being incorporated into the commercially available dentifrices.
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spelling doaj.art-1b68723095a047ee9c09536279b846302022-12-21T18:53:57ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74060976-48792012-01-014428228510.4103/0975-7406.103238Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trialPuneet GuptaNupur AgarwalN AnupB C ManujunathAnindya BhallaIntroduction: The growing field of alternative medicine has shown that dentifrices based on plant extracts are available in the market but there is little or no research to prove or refute the efficacy of dentifrices containing combination of herbal components. Aim: The study was conducted to evaluate the anti-plaque efficacy of a commercially available Meswak containing dentifrice compared to the conventional dentifrice using a randomized, triple blind, parallel design method. Materials and Methods: A total of 350 subjects were selected. All the subjects (aged 13-54 years) were given the test dentifrices, packed in plain white color-coded tubes. The subjects were instructed to brush their teeth twice daily for 2 min with the allocated dentifrice. The total study duration was 4 weeks. Plaque scores were recorded at the baseline, 2 weeks and 4 weeks respectively, using the Turesky modification of the Quigley Hein Plaque Index. Results: The results showed that there were significant differences in the reduction of plaque by the herbal dentifrice, Meswak (Salvadora persica) on intra-group and inter-group comparison. Conclusion: It was concluded that further research is required to know the dental benefits of herbal products being incorporated into the commercially available dentifrices.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=4;spage=282;epage=285;aulast=GuptaClinical trialherbal dentifricesMeswakplaque indexrandomized parallel designtriple blind study
spellingShingle Puneet Gupta
Nupur Agarwal
N Anup
B C Manujunath
Anindya Bhalla
Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial
Journal of Pharmacy and Bioallied Sciences
Clinical trial
herbal dentifrices
Meswak
plaque index
randomized parallel design
triple blind study
title Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial
title_full Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial
title_fullStr Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial
title_full_unstemmed Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial
title_short Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial
title_sort evaluating the anti plaque efficacy of meswak salvadora persica containing dentifrice a triple blind controlled trial
topic Clinical trial
herbal dentifrices
Meswak
plaque index
randomized parallel design
triple blind study
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=4;spage=282;epage=285;aulast=Gupta
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