Vitamin D influences gut microbiota and acetate production in zebrafish (Danio rerio) to promote intestinal immunity against invading pathogens

Vitamin D influences gut microbiota and acetate production in zebrafish (Danio rerio) to promote intestinal immunity against invading pathogens

ABSTRACTAlthough evidence has shown that vitamin D (VD) influences gut homeostasis, limited knowledge is available how VD regulates intestinal immunity against bacterial infection. In the present study, cyp2r1 mutant zebrafish, lacking the capacity to metabolize VD, and zebrafish fed a diet devoid o...

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Bibliographic Details
Main Authors: Xinmeng Liao, Yawen Lan, Wentao Wang, Jinjin Zhang, Rui Shao, Zhan Yin, Gudmundur H. Gudmundsson, Peter Bergman, Kangsen Mai, Qinghui Ai, Min Wan
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Short-chain fatty acids
microbiota
vitamin D3
antimicrobial peptides
IL-22
defensin
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2187575

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