The effect of high serum lipid level on benign gallbladder diseases
There is a positive correlation between serum lipid levels and benign gallbladder diseases. We wanted to evaluate whether there is a relationship between the preoperative lipid profiles results with the presence of cholesterolosis, cholesterol polyps and cholelithiasis in the pathological examinatio...
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| Format: | Article |
| Language: | English |
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Society of Turaz Bilim
2022-06-01
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| Series: | Medicine Science |
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| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=139839 |
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| author | Mikail Uyan Bayram Sen Medeni Arpa Oguzhan Okcu |
| author_facet | Mikail Uyan Bayram Sen Medeni Arpa Oguzhan Okcu |
| author_sort | Mikail Uyan |
| collection | DOAJ |
| description | There is a positive correlation between serum lipid levels and benign gallbladder diseases. We wanted to evaluate whether there is a relationship between the preoperative lipid profiles results with the presence of cholesterolosis, cholesterol polyps and cholelithiasis in the pathological examination. Patients who presented with various symptoms and underwent cholecystectomy surgery in a tertiary university hospital were retrospectively analyzed. Pathological examination records of 331 patients who had undergone cholecystectomy between 2016 and 2020 were obtained retrospectively. The latest lipid profiles results before the cholecystectomy were recorded. Patients were divided into groups according to their lipid profiles periods before cholecystectomy. The cholecystectomy reports of the patients were examined in terms of cholesterolosis, cholesterol polyp, and cholelithiasis. There was no difference between lipid profiles and the pathological subtypes in the patients whose lipid profiles were measured between 0-30 days and 0-90 days preoperatively. There was a significant difference in triglyceride levels between patients with cholesterol polyps and those without polyps, whose lipid profiles were measured within 90-180 days before surgery (p=0.031). There were significant differences in total cholesterol, triglyceride, LDL, and non-HDL levels between patients with and without cholesterolosis (p=0.017, p=0.037, p=0.048, p=0.019, respectively). There was a significant difference in triglyceride levels between patients with cholesterol polyps and those without polyps, whose lipid profiles were was measured within 0-180 days before surgery (p=0.023). There was a significant difference in total cholesterol, LDL, and non-HDL levels between patients with and without cholesterolosis (p=0.017, p=0.021, p=0.03, respectively). There is a positive correlation between preoperative serum lipid profiles and benign gallbladder diseases. The incidence of cholesterolosis and cholesterol polyps may increase after long-term exposure to high lipid concentrations. [Med-Science 2022; 11(2.000): 789-93] |
| first_indexed | 2024-03-08T06:42:57Z |
| format | Article |
| id | doaj.art-1b69aa0dca1b4e468a1651d5477c51ae |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T06:42:57Z |
| publishDate | 2022-06-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-1b69aa0dca1b4e468a1651d5477c51ae2024-02-03T08:19:14ZengSociety of Turaz BilimMedicine Science2147-06342022-06-011127899310.5455/medscience.2021.12.418139839The effect of high serum lipid level on benign gallbladder diseasesMikail Uyan0Bayram Sen1Medeni Arpa2Oguzhan Okcu3Recep Tayyip Erdoğan University Medical Faculty, Rize, Turkey Recep Tayyip Erdoğan University Medical Faculty, Rize, Turkey Recep Tayyip Erdoğan University Medical Faculty, Rize, Turkey Recep Tayyip Erdoğan University Medical Faculty, Rize, TurkeyThere is a positive correlation between serum lipid levels and benign gallbladder diseases. We wanted to evaluate whether there is a relationship between the preoperative lipid profiles results with the presence of cholesterolosis, cholesterol polyps and cholelithiasis in the pathological examination. Patients who presented with various symptoms and underwent cholecystectomy surgery in a tertiary university hospital were retrospectively analyzed. Pathological examination records of 331 patients who had undergone cholecystectomy between 2016 and 2020 were obtained retrospectively. The latest lipid profiles results before the cholecystectomy were recorded. Patients were divided into groups according to their lipid profiles periods before cholecystectomy. The cholecystectomy reports of the patients were examined in terms of cholesterolosis, cholesterol polyp, and cholelithiasis. There was no difference between lipid profiles and the pathological subtypes in the patients whose lipid profiles were measured between 0-30 days and 0-90 days preoperatively. There was a significant difference in triglyceride levels between patients with cholesterol polyps and those without polyps, whose lipid profiles were measured within 90-180 days before surgery (p=0.031). There were significant differences in total cholesterol, triglyceride, LDL, and non-HDL levels between patients with and without cholesterolosis (p=0.017, p=0.037, p=0.048, p=0.019, respectively). There was a significant difference in triglyceride levels between patients with cholesterol polyps and those without polyps, whose lipid profiles were was measured within 0-180 days before surgery (p=0.023). There was a significant difference in total cholesterol, LDL, and non-HDL levels between patients with and without cholesterolosis (p=0.017, p=0.021, p=0.03, respectively). There is a positive correlation between preoperative serum lipid profiles and benign gallbladder diseases. The incidence of cholesterolosis and cholesterol polyps may increase after long-term exposure to high lipid concentrations. [Med-Science 2022; 11(2.000): 789-93]http://www.ejmanager.com/fulltextpdf.php?mno=139839cholesterolosisgallbladdercholelithiasis |
| spellingShingle | Mikail Uyan Bayram Sen Medeni Arpa Oguzhan Okcu The effect of high serum lipid level on benign gallbladder diseases Medicine Science cholesterolosis gallbladder cholelithiasis |
| title | The effect of high serum lipid level on benign gallbladder diseases |
| title_full | The effect of high serum lipid level on benign gallbladder diseases |
| title_fullStr | The effect of high serum lipid level on benign gallbladder diseases |
| title_full_unstemmed | The effect of high serum lipid level on benign gallbladder diseases |
| title_short | The effect of high serum lipid level on benign gallbladder diseases |
| title_sort | effect of high serum lipid level on benign gallbladder diseases |
| topic | cholesterolosis gallbladder cholelithiasis |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=139839 |
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