Cytokine‐ and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy

Cytokine‐ and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy

Abstract Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment enriched with tumor cells, endothelial cells, immune cells, canc...

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Bibliographic Details
Main Authors: Ajaz A. Bhat, Sabah Nisar, Mayank Singh, Bazella Ashraf, Tariq Masoodi, Chandra P. Prasad, Atul Sharma, Selma Maacha, Thasni Karedath, Sheema Hashem, Syed Besina Yasin, Puneet Bagga, Ravinder Reddy, Michael P. Frennaux, Shahab Uddin, Punita Dhawan, Mohammad Haris, Muzafar A. Macha
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Cancer Communications
Subjects:
chemokine
colorectal cancer
cytokine
drug resistance
epithelial‐mesenchymal transition
immunosuppression
Online Access:https://doi.org/10.1002/cac2.12295

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