Lactococcin B Is Inactivated by Intrinsic Proteinase PrtP Digestion in Lactococcus lactis subsp. lactis BGMN1-501

Lactococcin B Is Inactivated by Intrinsic Proteinase PrtP Digestion in Lactococcus lactis subsp. lactis BGMN1-501

In our previous study we demonstrated that proteinase PrtP is able to impair bacteriocin LcnB activity, despite being produced by the same organism and encoded by the same plasmid. However, precise mechanism of this action, i.e., the exact cleavage site within LcnB bacteriocin, as well as its effect...

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Bibliographic Details
Main Authors: Goran Vukotic, Natalija Polovic, Nemanja Mirkovic, Branko Jovcic, Nemanja Stanisavljevic, Djordje Fira, Milan Kojic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Microbiology
Subjects:
proteinase PrtP
bacteriocin LcnB
hydrolysis
inactivation
Lactococcus lactis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00874/full

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