Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New Mexico
Post-traumatic stress disorder (PTSD), a common condition with potentially devastating individual, family, and societal consequences, is highly associated with substance use disorders (SUDs). The association between PTSD and SUD is complex and may involve adverse childhood experiences (ACEs), histor...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.905753/full |
| _version_ | 1811238948277583872 |
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| author | Snehal R. Bhatt Maya Armstrong Tassy Parker Tassy Parker Tassy Parker Tassy Parker Tassy Parker Marcello Maviglia Marcello Maviglia Rebecca Kass Lawrence Leeman Paul Romo Douglas Ziedonis |
| author_facet | Snehal R. Bhatt Maya Armstrong Tassy Parker Tassy Parker Tassy Parker Tassy Parker Tassy Parker Marcello Maviglia Marcello Maviglia Rebecca Kass Lawrence Leeman Paul Romo Douglas Ziedonis |
| author_sort | Snehal R. Bhatt |
| collection | DOAJ |
| description | Post-traumatic stress disorder (PTSD), a common condition with potentially devastating individual, family, and societal consequences, is highly associated with substance use disorders (SUDs). The association between PTSD and SUD is complex and may involve adverse childhood experiences (ACEs), historical and multi-generational traumas, and social determinants of health as well as cultural and spiritual contexts. Current psychosocial and pharmacological treatments for PTSD are only modestly effective, and there is a need for more research on therapeutic interventions for co-occurring PTSD and SUD, including whether to provide integrated or sequential treatments. There is a current resurgence of interest in psychedelics as potential treatment augmentation for PTSD and SUDs with an appreciation of the risks in this target population. This paper reviews the historical perspective of psychedelic research and practices, as well as the intersection of historical trauma, ACEs, PTSD, and SUDs through the lens of New Mexico. New Mexico is a state with high populations of Indigenous and Hispanic peoples as well as high rates of trauma, PTSD, and SUDs. Researchers in New Mexico have been leaders in psychedelic research. Future directions for psychedelic researchers to consider are discussed, including the importance of community-based participatory approaches that are more inclusive and respectful of Indigenous and other minority communities. |
| first_indexed | 2024-04-12T12:51:15Z |
| format | Article |
| id | doaj.art-1b747d9c48764fa1b981d9a4affc9048 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-12T12:51:15Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-1b747d9c48764fa1b981d9a4affc90482022-12-22T03:32:27ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-06-011310.3389/fphar.2022.905753905753Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New MexicoSnehal R. Bhatt0Maya Armstrong1Tassy Parker2Tassy Parker3Tassy Parker4Tassy Parker5Tassy Parker6Marcello Maviglia7Marcello Maviglia8Rebecca Kass9Lawrence Leeman10Paul Romo11Douglas Ziedonis12Department of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United StatesDepartment of Family and Community Medicine, University of New Mexico, Albuquerque, NM, United StatesDepartment of Family and Community Medicine, University of New Mexico, Albuquerque, NM, United StatesCollege of Nursing, University of New Mexico, Albuquerque, NM, United StatesCollege of Population Health, University of New Mexico, Albuquerque, NM, United StatesCenter for Native American Health, University of New Mexico, Albuquerque, NM, United StatesAmerican Indian Health Research and Education, University of New Mexico, Albuquerque, NM, United StatesDepartment of Family and Community Medicine, University of New Mexico, Albuquerque, NM, United StatesCenter for Native American Health, University of New Mexico, Albuquerque, NM, United StatesDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United StatesDepartment of Family and Community Medicine, University of New Mexico, Albuquerque, NM, United StatesDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United StatesExecutive Vice President, University of New Mexico Health Sciences Center, Albuquerque, NM, United StatesPost-traumatic stress disorder (PTSD), a common condition with potentially devastating individual, family, and societal consequences, is highly associated with substance use disorders (SUDs). The association between PTSD and SUD is complex and may involve adverse childhood experiences (ACEs), historical and multi-generational traumas, and social determinants of health as well as cultural and spiritual contexts. Current psychosocial and pharmacological treatments for PTSD are only modestly effective, and there is a need for more research on therapeutic interventions for co-occurring PTSD and SUD, including whether to provide integrated or sequential treatments. There is a current resurgence of interest in psychedelics as potential treatment augmentation for PTSD and SUDs with an appreciation of the risks in this target population. This paper reviews the historical perspective of psychedelic research and practices, as well as the intersection of historical trauma, ACEs, PTSD, and SUDs through the lens of New Mexico. New Mexico is a state with high populations of Indigenous and Hispanic peoples as well as high rates of trauma, PTSD, and SUDs. Researchers in New Mexico have been leaders in psychedelic research. Future directions for psychedelic researchers to consider are discussed, including the importance of community-based participatory approaches that are more inclusive and respectful of Indigenous and other minority communities.https://www.frontiersin.org/articles/10.3389/fphar.2022.905753/fullPTSDpsychedelicsadverse childhood experiencessocial determinants of healthAI/AN healthsubstance use |
| spellingShingle | Snehal R. Bhatt Maya Armstrong Tassy Parker Tassy Parker Tassy Parker Tassy Parker Tassy Parker Marcello Maviglia Marcello Maviglia Rebecca Kass Lawrence Leeman Paul Romo Douglas Ziedonis Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New Mexico Frontiers in Pharmacology PTSD psychedelics adverse childhood experiences social determinants of health AI/AN health substance use |
| title | Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New Mexico |
| title_full | Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New Mexico |
| title_fullStr | Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New Mexico |
| title_full_unstemmed | Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New Mexico |
| title_short | Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead From New Mexico |
| title_sort | psychedelic therapies at the crossroads of trauma and substance use historical perspectives and future directions taking a lead from new mexico |
| topic | PTSD psychedelics adverse childhood experiences social determinants of health AI/AN health substance use |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.905753/full |
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