Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate
Isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate (<b>1</b>) was obtained from the 2-methyl-6-nitrobenzoic anhydride (MNBA)/4-dimethylaminopyridine (DMAP)-catalyzed reaction at room temperature for 190 min in dichloromethane with a yield of 95%. The structure of isoamyl (<...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Molbank |
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| Online Access: | https://www.mdpi.com/1422-8599/2023/3/M1708 |
| _version_ | 1797578652246867968 |
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| author | Egar Pamela Lukman Atmaja Mardi Santoso |
| author_facet | Egar Pamela Lukman Atmaja Mardi Santoso |
| author_sort | Egar Pamela |
| collection | DOAJ |
| description | Isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate (<b>1</b>) was obtained from the 2-methyl-6-nitrobenzoic anhydride (MNBA)/4-dimethylaminopyridine (DMAP)-catalyzed reaction at room temperature for 190 min in dichloromethane with a yield of 95%. The structure of isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate (<b>1</b>) was elucidated using NMR, FTIR, and high-resolution mass spectrometry. In vitro sun protection factor evaluation exhibited a value of 37.10 ± 0.03 which indicates that isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate (<b>1</b>) is a sunscreen agent with high protection. |
| first_indexed | 2024-03-10T22:25:48Z |
| format | Article |
| id | doaj.art-1b7cd1fc84774941abf69261f5cbe861 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-03-10T22:25:48Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-1b7cd1fc84774941abf69261f5cbe8612023-11-19T12:06:57ZengMDPI AGMolbank1422-85992023-08-0120233M170810.3390/M1708Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylateEgar Pamela0Lukman Atmaja1Mardi Santoso2Department of Chemistry, Faculty of Science and Analytical Data, Institut Teknologi Sepuluh Nopember, Kampus ITS Sukolilo, Surabaya 60111, IndonesiaDepartment of Chemistry, Faculty of Science and Analytical Data, Institut Teknologi Sepuluh Nopember, Kampus ITS Sukolilo, Surabaya 60111, IndonesiaDepartment of Chemistry, Faculty of Science and Analytical Data, Institut Teknologi Sepuluh Nopember, Kampus ITS Sukolilo, Surabaya 60111, IndonesiaIsoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate (<b>1</b>) was obtained from the 2-methyl-6-nitrobenzoic anhydride (MNBA)/4-dimethylaminopyridine (DMAP)-catalyzed reaction at room temperature for 190 min in dichloromethane with a yield of 95%. The structure of isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate (<b>1</b>) was elucidated using NMR, FTIR, and high-resolution mass spectrometry. In vitro sun protection factor evaluation exhibited a value of 37.10 ± 0.03 which indicates that isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate (<b>1</b>) is a sunscreen agent with high protection.https://www.mdpi.com/1422-8599/2023/3/M1708synthesisisoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylatesun protection factor |
| spellingShingle | Egar Pamela Lukman Atmaja Mardi Santoso Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate Molbank synthesis isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate sun protection factor |
| title | Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate |
| title_full | Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate |
| title_fullStr | Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate |
| title_full_unstemmed | Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate |
| title_short | Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate |
| title_sort | isoamyl i e i 3 3 4 dimethoxyphenyl acrylate |
| topic | synthesis isoamyl (<i>E</i>)-3-(3,4-dimethoxyphenyl)acrylate sun protection factor |
| url | https://www.mdpi.com/1422-8599/2023/3/M1708 |
| work_keys_str_mv | AT egarpamela isoamyliei334dimethoxyphenylacrylate AT lukmanatmaja isoamyliei334dimethoxyphenylacrylate AT mardisantoso isoamyliei334dimethoxyphenylacrylate |