Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative study
Abstract Background There is preliminary evidence suggesting that FCR is a major problem for breast cancer survivors carrying a BRCA1/2 mutation. The goal of this qualitative study, conducted among women who were treated for breast cancer, was to provide a deeper understanding of how FCR is experien...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.6889 |
| _version_ | 1797277132171247616 |
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| author | Josée Savard Catherine Filion Claudia Mc Brearty Aude Caplette‐Gingras Jocelyne Chiquette Michel Dorval |
| author_facet | Josée Savard Catherine Filion Claudia Mc Brearty Aude Caplette‐Gingras Jocelyne Chiquette Michel Dorval |
| author_sort | Josée Savard |
| collection | DOAJ |
| description | Abstract Background There is preliminary evidence suggesting that FCR is a major problem for breast cancer survivors carrying a BRCA1/2 mutation. The goal of this qualitative study, conducted among women who were treated for breast cancer, was to provide a deeper understanding of how FCR is experienced in the context of a genetic predisposition to breast cancer. Method Three focus groups (90–110 min) were conducted with 19 breast cancer survivors carrying a BRCA1/2 mutation. The semistructured interview probed FCR level and impact, the role FCR played in the decision to have a prophylactic bilateral mastectomy and/or salpingo‐oophorectomy, the effect that surgery had on FCR, and the relevance of offering a psychological intervention targeting FCR to this population. Results Findings indicated that FCR was a significant issue in these women, even though a majority had undergone a prophylactic surgery. Patients strongly affirmed the need to develop and provide access to FCR interventions that are specifically adapted to the needs of this group. Discussion These results suggest that, although being the most effective medical option to reduce the actual risk of local recurrence (or second breast cancer), prophylactic surgery only partially reduces FCR. A psychological intervention targeting specifically FCR would be an appropriate complement to preventive surgery. |
| first_indexed | 2024-03-07T15:43:15Z |
| format | Article |
| id | doaj.art-1b7e561268e54f75a13a74567c084c75 |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-03-07T15:43:15Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-1b7e561268e54f75a13a74567c084c752024-03-05T06:22:52ZengWileyCancer Medicine2045-76342024-01-01131n/an/a10.1002/cam4.6889Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative studyJosée Savard0Catherine Filion1Claudia Mc Brearty2Aude Caplette‐Gingras3Jocelyne Chiquette4Michel Dorval5School of Psychology Université Laval Québec Québec CanadaCentre de recherche du CHU de Québec‐Université Laval Québec Québec CanadaSchool of Psychology Université Laval Québec Québec CanadaCentre de recherche du CHU de Québec‐Université Laval Québec Québec CanadaCentre de recherche du CHU de Québec‐Université Laval Québec Québec CanadaUniversité Laval Cancer Research Center Québec Québec CanadaAbstract Background There is preliminary evidence suggesting that FCR is a major problem for breast cancer survivors carrying a BRCA1/2 mutation. The goal of this qualitative study, conducted among women who were treated for breast cancer, was to provide a deeper understanding of how FCR is experienced in the context of a genetic predisposition to breast cancer. Method Three focus groups (90–110 min) were conducted with 19 breast cancer survivors carrying a BRCA1/2 mutation. The semistructured interview probed FCR level and impact, the role FCR played in the decision to have a prophylactic bilateral mastectomy and/or salpingo‐oophorectomy, the effect that surgery had on FCR, and the relevance of offering a psychological intervention targeting FCR to this population. Results Findings indicated that FCR was a significant issue in these women, even though a majority had undergone a prophylactic surgery. Patients strongly affirmed the need to develop and provide access to FCR interventions that are specifically adapted to the needs of this group. Discussion These results suggest that, although being the most effective medical option to reduce the actual risk of local recurrence (or second breast cancer), prophylactic surgery only partially reduces FCR. A psychological intervention targeting specifically FCR would be an appropriate complement to preventive surgery.https://doi.org/10.1002/cam4.6889BRCA1/2 genetic mutationbreast cancerfear of cancer recurrencepsychological interventionqualitative study |
| spellingShingle | Josée Savard Catherine Filion Claudia Mc Brearty Aude Caplette‐Gingras Jocelyne Chiquette Michel Dorval Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative study Cancer Medicine BRCA1/2 genetic mutation breast cancer fear of cancer recurrence psychological intervention qualitative study |
| title | Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative study |
| title_full | Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative study |
| title_fullStr | Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative study |
| title_full_unstemmed | Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative study |
| title_short | Fear of cancer recurrence in breast cancer survivors carrying a BRCA1/2 mutation: A qualitative study |
| title_sort | fear of cancer recurrence in breast cancer survivors carrying a brca1 2 mutation a qualitative study |
| topic | BRCA1/2 genetic mutation breast cancer fear of cancer recurrence psychological intervention qualitative study |
| url | https://doi.org/10.1002/cam4.6889 |
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