A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast
Cellular aging is a multifactorial process that is characterized by a decline in homeostatic capacity, best described at the molecular level. Physicochemical properties such as pH and macromolecular crowding are essential to all molecular processes in cells and require maintenance. Whether a drift i...
Main Authors: | Sara N Mouton, David J Thaller, Matthew M Crane, Irina L Rempel, Owen T Terpstra, Anton Steen, Matt Kaeberlein, C Patrick Lusk, Arnold J Boersma, Liesbeth M Veenhoff |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/54707 |
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